Dyshidrotic Eczema: This condition is characterized by small, itchy blisters on the hands and feet, often accompanied by dryness and cracking of the skin. It's a common condition that can be triggered by stress, allergies, or environmental factors.

Contact Dermatitis: An itchy rash on the hands and feet could be due to an allergic reaction or irritation from substances like soaps, detergents, or certain metals.
Atopic Dermatitis (Eczema): While more common in children, atopic dermatitis can occur in adults and may present with itchy rashes on the hands and feet, among other areas.
Psoriasis: This chronic skin condition can cause itchy, scaly patches on various parts of the body, including the hands and feet.
Scabies: A parasitic infection caused by the scabies mite, leading to intense itching and a pustular rash, which can affect the hands and feet, especially in infants and young children.

Pemphigus: A rare autoimmune disease that causes blistering of the skin and mucous membranes. While less common, it's critical to diagnose early due to its potential severity.
Cutaneous T-Cell Lymphoma (Mycosis Fungoides): A type of skin cancer that can present with skin patches, plaques, or rashes, including on the hands and feet. Early diagnosis is crucial for effective treatment.
Syphilis (Secondary): This stage of syphilis can cause a variety of skin rashes, including on the palms of the hands and soles of the feet, making it a critical diagnosis not to miss due to its implications for public health and the individual's health.

Keratoderma Blennorrhagicum: Associated with reactive arthritis, this condition causes skin lesions on the hands and feet that resemble psoriasis.
Pityriasis Rubra Pilaris: A rare skin disorder characterized by constant itching and scaling (exfoliation) of the skin, which can include the hands and feet.
Erythema Multiforme: An immune-mediated disorder that can cause target-like lesions on the skin, including the hands and feet, often in response to infections or medications.