What are the symptoms of Fibromyalgia (Fibromyalgia syndrome)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 10, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Fibromyalgia is characterized by a complex array of symptoms including widespread chronic pain, fatigue, sleep disturbances, and cognitive difficulties, as highlighted in the 2017 EULAR revised recommendations for the management of fibromyalgia 1. The primary symptoms include:

  • Persistent pain throughout the body, particularly in muscles and soft tissues, often described as a constant dull ache
  • Extreme fatigue that isn't relieved by rest, along with sleep problems such as waking unrefreshed despite adequate sleep time
  • Cognitive symptoms, sometimes called "fibro fog," include difficulty concentrating, memory problems, and mental cloudiness
  • Heightened sensitivity to touch, temperature, light, and sound Additional common symptoms include:
  • Headaches
  • Irritable bowel syndrome
  • Painful menstrual periods
  • Numbness or tingling in hands and feet
  • Restless leg syndrome
  • Mood issues like anxiety and depression These symptoms often fluctuate in intensity, with certain triggers like stress, weather changes, or physical exertion causing flare-ups, as noted in the EULAR recommendations 1. The symptoms of fibromyalgia result from central sensitization, where the brain and spinal cord process pain signals abnormally, amplifying sensations and causing the body to overreact to stimuli that wouldn't normally cause pain, which is a key aspect of the condition's complex and heterogeneous nature 1. The management of fibromyalgia should aim at improving health-related quality of life, balancing benefit and risk of treatment, and often requires a multidisciplinary approach with a combination of non-pharmacological and pharmacological treatment modalities, as recommended by the EULAR guidelines 1.

From the Research

Symptoms of Fibromyalgia

The symptoms of Fibromyalgia syndrome include:

  • Chronic generalized pain 2, 3, 4, 5, 6
  • Fatigue 2, 3, 4, 5, 6
  • Sleep disturbances 2, 3, 4, 5, 6
  • Stiffness 2, 4
  • Cognitive impairment 2
  • Psychological distress 2
  • Heightened sensitivity 4
  • Morning stiffness 4
  • Decreased volition 4
  • Depressed mood 4
  • Headaches 5
  • Mental fog 5
  • Mood swings 5

Common Characteristics

Fibromyalgia is characterized by:

  • Widespread musculoskeletal pain 3, 4, 6
  • Chronic medical condition with physical, psychiatric, and psychological symptoms 4
  • Complex and different symptoms reported by patients 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

An update on pharmacotherapy for the treatment of fibromyalgia.

Expert opinion on pharmacotherapy, 2015

Research

Complementary and alternative therapies for fibromyalgia.

Current rheumatology reports, 2001

Research

Diet and Lifestyle Modifications for Fibromyalgia.

Current rheumatology reviews, 2024

Research

Pharmacological treatment of fibromyalgia.

Clinical and experimental rheumatology, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.