ADHD Treatment Algorithm for Children
For children with ADHD, treatment should follow an age-specific algorithm that includes FDA-approved medications along with behavioral interventions, with medication being the primary intervention for school-aged children and adolescents. 1
Age-Specific Treatment Recommendations
Preschool Children (4-5 years)
First-line: Evidence-based parent and/or teacher-administered behavioral therapy 2
- Parent training in behavior management (PTBM)
- Behavioral classroom interventions when available
Second-line: Consider methylphenidate if:
Elementary and Middle School Children (6-12 years)
First-line: FDA-approved medications for ADHD 2
- Strongest evidence for stimulants (methylphenidate or amphetamine derivatives)
- Sufficient but less strong evidence for non-stimulants in this order:
- Atomoxetine
- Extended-release guanfacine
- Extended-release clonidine
- Starting dose for methylphenidate: 5 mg twice daily (immediate-release) or 10 mg once daily (extended-release) 3
Concurrent behavioral interventions:
- Parent training in behavior management
- Behavioral classroom interventions
- Educational supports (IEP or 504 plan) 2
Adolescents (12-18 years)
First-line: FDA-approved medications for ADHD with adolescent's assent 2
- Similar medication options as for school-age children
- Maximum recommended daily dose of methylphenidate: 60 mg 3
Concurrent interventions:
Medication Management
- Titrate doses to achieve maximum benefit with minimum adverse effects 2
- Follow-up within 2-4 weeks after medication adjustments 1
- Monitor for side effects:
- Cardiovascular effects
- Weight changes
- Sleep disturbances
- Development of tics or psychiatric symptoms 1
- For adults/adolescents who have sleep difficulties, administer last dose before 6 p.m. 3
Behavioral Interventions
- Parent Training: Teaches behavior modification principles for home implementation (median effect size: 0.55) 2
- Classroom Management: Provides behavior modification strategies for teachers (median effect size: 0.61) 2
- Organizational Skills Training: Addresses time management and planning deficits 1
Important Considerations
- Screen for and address comorbid conditions that may complicate treatment 2, 1
- Recognize ADHD as a chronic condition requiring ongoing management 2
- Involve schools in treatment planning for comprehensive care 1
- Store methylphenidate in a safe place due to abuse potential 3
Common Pitfalls to Avoid
- Failing to screen for comorbid conditions that may require additional interventions
- Inadequate medication monitoring and dose adjustment
- Not involving schools in treatment planning
- Using medication as first-line therapy for preschoolers instead of behavioral interventions
- Neglecting to plan for transition to adult care for adolescents
The evidence strongly supports a multimodal approach combining medication (for ages 6+) with behavioral interventions, with the specific components tailored to the child's age and developmental needs.