What is the procedure for completing a Patent Ductus Arteriosus (PDA) operation?

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From the Guidelines

Percutaneous catheter closure is the recommended procedure for completing a Patent Ductus Arteriosus (PDA) operation in adults, due to its high success rate and minimal complications, as stated in the 2018 AHA/ACC guideline for the management of adults with congenital heart disease 1.

Procedure Overview

The procedure for completing a PDA operation involves either surgical ligation or catheter-based closure.

  • Surgical ligation requires a thoracotomy, allowing the surgeon to access the ductus arteriosus, which is then tied off with sutures or closed with clips.
  • The catheter-based approach is less invasive and involves inserting a catheter through a blood vessel in the groin, guiding it to the heart, and deploying a closure device to seal the PDA.

Choice of Procedure

The choice between procedures depends on the patient's age, PDA size, and anatomy, as well as the presence of other conditions that may require surgical correction.

  • Percutaneous closure is generally preferred in adults due to its lower risk of complications and faster recovery time 1.
  • Surgical closure may be necessary in cases where the PDA is too large for device closure or where there are other conditions that require surgical correction.

Considerations

When considering PDA closure, it is essential to assess the patient's overall health and the presence of any other conditions that may affect the outcome of the procedure.

  • Invasive hemodynamic assessment may be necessary to evaluate pulmonary vasoreactivity and determine the best course of treatment 1.
  • Consultation with ACHD and pulmonary hypertension providers is crucial in complex cases, such as those with elevated pulmonary pressure and net right-to-left shunting.

From the Research

Procedure for Completing a Patent Ductus Arteriosus (PDA) Operation

The procedure for completing a PDA operation involves several steps and considerations, including:

  • Medical management, which may include the use of non-steroid anti-inflammatory drugs (NSAIDs) such as indomethacin or ibuprofen to promote closure of the ductus arteriosus 2, 3, 4
  • Surgical ligation, which is typically considered if pharmacological treatment fails to close the PDA in symptomatic infants 4, 5
  • Transcatheter device closure, which is a minimally invasive procedure that can be used to close the PDA 5

Treatment Options

The treatment options for PDA include:

  • Pharmacological treatment with NSAIDs, such as indomethacin or ibuprofen, which can be effective in promoting closure of the ductus arteriosus 2, 3, 4
  • Surgical ligation, which is typically considered if pharmacological treatment fails to close the PDA in symptomatic infants 4, 5
  • Transcatheter device closure, which is a minimally invasive procedure that can be used to close the PDA 5
  • Acetaminophen, which has been suggested as a promising new alternative to indomethacin and ibuprofen for closure of PDA with potentially fewer adverse effects 6

Considerations

The choice of treatment for PDA depends on several factors, including:

  • The severity of the PDA and the presence of symptoms 3, 4
  • The gestational age and birth weight of the infant 2, 4
  • The presence of other medical conditions or complications 3, 4
  • The potential risks and benefits of each treatment option 3, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Non-steroid anti-inflammatory drugs in the treatment of patent ductus arteriosus in European newborns.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2009

Research

Treatment of patent ductus arteriosus: indomethacin or ibuprofen?

Journal of perinatology : official journal of the California Perinatal Association, 2008

Research

Use of acetaminophen for patent ductus arteriosus treatment: a single center experience.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2020

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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