What is the treatment for a wasp sting?

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Treatment for Wasp Stings

For a typical wasp sting, treatment should include immediate cleaning with soap and water, application of a cold compress to reduce pain and swelling, and use of oral analgesics such as acetaminophen for pain control. 1

Initial Management

  1. Clean the sting site thoroughly:

    • Wash with soap and water
    • Perform irrigation with normal saline if available 1
  2. Reduce pain and swelling:

    • Apply a cold compress or ice pack to the area (place a thin barrier between ice and skin) 1
    • Consider topical 2.5% lidocaine ointment for local pain relief 1
    • Use oral acetaminophen for pain control 1
  3. Manage local reactions:

    • Elevate the affected limb if significant swelling is present 1
    • Antihistamines may help reduce itching and swelling 1, 2
    • Topical corticosteroid lotions can help with inflammation 2

Severe Reactions Management

For patients experiencing anaphylaxis (a life-threatening emergency):

  1. Administer epinephrine immediately:

    • Epinephrine (IM) is the first-line treatment for anaphylaxis resulting from insect stings 3
    • Signs of anaphylaxis include flushing, syncope, tachycardia, hypotension, airway swelling, bronchospasm, urticaria, and angioedema 3
  2. Monitor vital signs and be prepared to provide additional supportive care:

    • Onset of anaphylactic signs typically occurs within 10 minutes of the sting 2
    • Prompt recognition and treatment is critical for successful management 2

Special Considerations

  • Patients with history of systemic reactions should:

    • Carry self-injectable epinephrine and know how to use it 1
    • Consider obtaining medical identification jewelry 1
    • Be referred to an allergist-immunologist for evaluation 1
    • Consider venom immunotherapy (VIT) if they have positive specific IgE tests 1
  • Multiple stings can lead to more severe reactions including:

    • Vomiting, diarrhea, dyspnea, generalized edema, hypotension 4
    • Rarely, serious complications like stroke and multi-organ dysfunction 4
    • The estimated lethal dose is approximately 20 stings/kg in most mammals 2

When to Seek Medical Attention

  • Immediate medical attention is required for:

    • Signs of anaphylaxis (difficulty breathing, throat tightness, dizziness, widespread hives)
    • Multiple stings, especially in children, elderly, or those with underlying health conditions
    • Stings in the mouth, throat, or eyes
  • Follow-up care should be considered:

    • Monitor the bite site for 48-72 hours for signs of infection 1
    • Follow-up within 24-48 hours to assess response to treatment 1
    • Watch for signs of secondary infection (increasing redness, warmth, pain, purulent drainage) 1

Prevention

  • Wear protective clothing (long sleeves, pants) especially during dusk and dawn 1
  • Use DEET-containing repellents (10-30%) 1
  • Avoid bright colors and strong scents 1
  • Use screens on windows and doors 1
  • Remove nests and avoid areas with standing water 1

Clinical Pearls

  • Unlike bees, wasps can sting multiple times as they do not lose their stinger 2
  • Anaphylactic reactions to stings are not dose-dependent or related to the number of stings 2
  • Mastocytosis is found in 3-5% of patients with sting anaphylaxis, making these patients prone to very severe reactions 5
  • Most patients with systemic anaphylactic reactions to wasp stings need specific immunotherapy to prevent future reactions 5

References

Guideline

Management of Animal Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Hymenoptera stings.

Clinical techniques in small animal practice, 2006

Research

Insect stings: clinical features and management.

Deutsches Arzteblatt international, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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