Differential Diagnosis for cUTI and uUTI
Single Most Likely Diagnosis
- Uncomplicated Urinary Tract Infection (UTI): This is the most common cause of symptoms such as dysuria, frequency, and urgency in patients presenting with cUTI or uUTI. The typical pathogens include E. coli, Klebsiella, Proteus, and Enterococcus.
Other Likely Diagnoses
- Complicated Urinary Tract Infection (cUTI): Involves structural or functional abnormalities of the urinary tract, or the presence of an indwelling catheter, which increases the risk of infection with more resistant organisms.
- Pyelonephritis: An infection of the upper urinary tract, which can present with flank pain, fever, and chills, in addition to the symptoms of a lower UTI.
- Urethritis: Inflammation of the urethra, which can be caused by infectious or non-infectious agents, presenting with dysuria and urethral discharge.
Do Not Miss Diagnoses
- Sepsis: A life-threatening condition that can arise from an untreated or inadequately treated UTI, especially in patients with underlying health conditions or compromised immune systems.
- Obstructive Uropathy: Conditions such as kidney stones or tumors that can cause urinary retention and increase the risk of infection, which if missed, can lead to severe consequences including kidney damage.
- Emphysematous Pyelonephritis: A rare but serious infection of the kidney characterized by gas formation, typically occurring in diabetic patients, which requires prompt recognition and treatment.
Rare Diagnoses
- Tuberculosis of the Urinary Tract: A rare cause of UTI symptoms, characterized by chronic infection with Mycobacterium tuberculosis, which can lead to significant morbidity if not recognized and treated appropriately.
- Fungal UTI: Uncommon infections caused by fungi such as Candida, typically seen in patients with specific risk factors such as immunocompromised states or indwelling catheters.
- Parasitic Infections: Such as schistosomiasis, which can cause urinary tract symptoms and is seen in specific geographic locations or in travelers to endemic areas.