Can inflammation directly cause anorgasmia (inability to achieve orgasm)?

From the Research

Inflammation and Anorgasmia

• There is evidence to suggest that inflammation may interfere with female sexual desire and arousal, which could potentially contribute to anorgasmia 1.
• Inflammation-related conditions, such as cardiovascular disease, metabolic syndrome, and chronic pain, are associated with an increased risk of female sexual dysfunction, including anorgasmia 1.
• However, the precise nature of the association between inflammation and anorgasmia remains unclear 1.

Direct Cause of Anorgasmia

• There is no direct evidence to suggest that inflammation can directly cause anorgasmia 1, 2, 3, 4, 5.
• Anorgasmia is often associated with psychological, neurological, or drug-related factors, rather than inflammation alone 2, 3, 5.

Related Factors

• Arousal difficulty and lubrication difficulty are predictors of difficulty reaching orgasm in women, which may be related to inflammation 4.
• Certain medications, such as serotoninergic drugs and alpha-blockers, can induce delayed orgasm or anorgasmia, which may be related to inflammation 3, 5.