From the Research
Antopol-Goldman lesions are a rare condition characterized by renal pelvic subepithelial hematoma, often simulating a neoplastic process, and should be considered in the differential diagnosis of macroscopic hematuria. This condition is also known as a spontaneous renal pelvic subepithelial hematoma, and it can be mistaken for renal tumors, leading to unnecessary nephrectomy 1. The causes of Antopol-Goldman lesions are not well established, but multiple factors have been linked, and radiology is the cornerstone for diagnosis 1.
Key Characteristics
- Renal pelvic subepithelial hematoma or hemorrhage
- Sporadic disease with uncertain causes
- May be mistaken for renal tumors
- Radiology is crucial for diagnosis
- Can be treated conservatively or with partial nephrectomy
Clinical Implications
- Antopol-Goldman lesions can present with gross hematuria and flank pain, as seen in a 17-year-old male who was diagnosed with the condition 1
- The lesion can be visualized as a filling defect in the renal pelvis on CT scans, as reported in a case study of an 86-year-old woman 2
- Awareness of Antopol-Goldman lesions is essential to avoid unnecessary nephrectomy, as highlighted in a study published in the Indian Journal of Pathology & Microbiology 3