Does a history of prophylactic mastectomy with Deep Inferior Epigastric Perforator (DIEP) reconstruction complicate surgery to retrieve a living donor kidney?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 27, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Impact of Prior DIEP Reconstruction on Living Donor Kidney Retrieval

Prior prophylactic mastectomy with DIEP flap reconstruction does not significantly complicate living donor kidney retrieval surgery when performed by experienced surgeons, though special surgical planning is required.

Anatomical Considerations and Surgical Planning

The Deep Inferior Epigastric Perforator (DIEP) flap reconstruction uses abdominal tissue and blood vessels that may overlap with the surgical field for kidney donation. Key considerations include:

  • DIEP flap harvest involves dissection of the deep inferior epigastric vessels and perforators from the lower abdominal wall 1, 2
  • Living donor kidney retrieval typically uses laparoscopic or "mini-open" approaches as recommended by the American College of Kidney Diseases 3, 4
  • Preoperative imaging is essential - CT angiography is mandatory to assess both renal anatomy and previous surgical changes to the abdominal wall vasculature 3, 4

Surgical Approach Modifications

The standard approach may need modification:

  • The left kidney is generally preferred for laparoscopic donor nephrectomy due to the longer venous pedicle 4
  • Previous DIEP reconstruction may necessitate adjustments to port placement during laparoscopy to avoid areas of previous dissection
  • Hand-assisted laparoscopy or "mini-open" techniques remain viable options with appropriate planning 3
  • Traditional open nephrectomy may be considered if extensive adhesions are anticipated, though this should be a last resort 4

Potential Complications

While DIEP flap surgery itself has a low complication rate (0.6% total flap loss) 1, 2, several considerations exist for subsequent kidney donation:

  • Abdominal wall weakness or hernia is rare after DIEP (0.2% in large series) 1 but could affect surgical approach
  • Altered abdominal wall vasculature may require careful dissection
  • Previous abdominal surgery increases the risk of adhesions that could complicate laparoscopic access

Perioperative Management

Special attention should be paid to:

  • Thorough preoperative evaluation including detailed imaging of both renal anatomy and previous surgical changes 4
  • Selection of surgeons with adequate experience in complex donor nephrectomy 3
  • Appropriate anesthetic management with consideration of regional techniques for pain control 4
  • Careful perioperative discontinuation of any dietary supplements that may increase bleeding risk 3

Conclusion

With proper preoperative planning, imaging, and experienced surgical teams, prior DIEP flap reconstruction should not be a contraindication to living kidney donation. The key is thorough evaluation of the abdominal wall anatomy and appropriate surgical approach selection based on the individual's specific anatomical considerations.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.