What are the differential diagnoses for measles (rubeola)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 11, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Measles Differential Diagnosis

The differential diagnosis for measles includes various infectious and non-infectious conditions that present with similar symptoms. Here's a categorized list of potential diagnoses:

  • Single most likely diagnosis
    • Measles: The most likely diagnosis, given the classic symptoms of fever, cough, runny nose, conjunctivitis, and a characteristic rash.
  • Other Likely diagnoses
    • Rubella (German measles): Presents with similar symptoms, including a rash and fever, but is typically milder than measles.
    • Roseola: A viral illness that causes a high fever and a rash, often seen in young children.
    • Scarlet fever: An infectious disease caused by group A streptococcus, characterized by a rash, fever, and sore throat.
    • Kawasaki disease: An acute febrile illness that affects children, causing a rash, fever, and lymphadenopathy.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Meningitis: A potentially life-threatening infection that can present with fever, headache, and rash.
    • Sepsis: A severe and potentially fatal condition that can cause fever, rash, and organ dysfunction.
    • Rocky Mountain spotted fever: A tick-borne illness that can cause fever, rash, and severe complications if left untreated.
    • Toxic shock syndrome: A rare but life-threatening condition caused by bacterial toxins, characterized by fever, rash, and hypotension.
  • Rare diagnoses
    • Erythema infectiosum (Fifth disease): A mild viral illness that causes a distinctive "slapped-cheek" rash.
    • Enteroviral infections: A group of viral illnesses that can cause a range of symptoms, including fever, rash, and respiratory issues.
    • Adenoviral infections: A common viral illness that can cause a range of symptoms, including fever, rash, and respiratory issues.
    • Parvovirus B19 infection: A viral illness that can cause a range of symptoms, including fever, rash, and anemia.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.