Management of Concussion Headaches
For concussion headaches, ibuprofen (400-800 mg) or acetaminophen (1000 mg) should be used as first-line treatment, with alternating both medications providing superior relief compared to either medication alone. 1, 2
First-Line Pharmacologic Management
Acetaminophen and NSAIDs:
- Ibuprofen 400-800 mg every 6-8 hours (not exceeding 2400 mg daily)
- Acetaminophen 1000 mg every 6 hours (not exceeding 4000 mg daily)
- Note: Lower doses of acetaminophen (500-650 mg) have not shown statistically significant improvement 2
- Consider alternating ibuprofen and acetaminophen for enhanced efficacy 1
Important caution: Limit analgesic use to 2-3 days per week to prevent medication overuse headache, which can paradoxically worsen concussion headaches 3
Non-Pharmacologic Approaches
Physical Therapy: Beneficial for headache management with a "weak for" recommendation 2
- Combination of thermal methods, trigger point massage, and mobilization/manipulation techniques
- More effective than sham interventions or medications alone for reducing headache frequency and intensity
Exercise Therapy: Recommended with a "weak for" recommendation 2
- Aerobic exercise 2-3 times weekly for 30-60 minutes
- Upper-body progressive strength training 3 times weekly for 30 minutes
- Benefits include improved headache control, weight management, and reduced vascular risk
Management Algorithm
Initial Treatment:
- Start with ibuprofen 400-800 mg OR acetaminophen 1000 mg for mild to moderate headaches
- For severe headaches, consider alternating both medications
If Initial Treatment Fails:
- For persistent headaches, consider referral to physical therapy
- Add aerobic exercise program when symptoms allow
- Evaluate for medication overuse headache if symptoms persist beyond 3 months
For Refractory Cases:
- Consider metoclopramide for headaches with associated nausea 4
- Evaluate for other headache types (migraine, tension-type) that may require specific treatment
- Consider neurology referral for persistent symptoms beyond 3 months
Special Considerations
Medication Overuse Risk: Monitor analgesic use carefully, as overuse can lead to chronic post-traumatic headaches 3
- Educate patients to limit analgesic use to prevent this complication
- If medication overuse is suspected, implement analgesic detoxification
Timing of Intervention: Early intervention with appropriate analgesia may decrease persistent symptoms 5
Monitoring: Track headache frequency, intensity, and medication use with a headache diary
Return to Activity: Patients using both ibuprofen and acetaminophen (79%) or ibuprofen alone (61%) were more likely to return to school within one week compared to acetaminophen alone (33.3%) or standard care without analgesics (21.1%) 1
The evidence suggests that proper analgesic management, combined with appropriate non-pharmacologic therapies, can effectively manage concussion headaches while minimizing the risk of medication overuse headache and facilitating faster return to normal activities.