STD Screening Recommendations for 16-Year-Olds
All sexually active 16-year-olds should be screened annually for chlamydia and gonorrhea, with females requiring routine screening regardless of reported risk factors and males requiring screening based on risk factors and in high-prevalence settings. 1, 2
Core Screening Recommendations by Gender
For Females (16 years old)
- Chlamydia: Annual screening for all sexually active females ≤25 years 1, 2
- Gonorrhea: Annual screening for all sexually active females ≤25 years 1, 2
- HIV: Screen if engaging in high-risk sexual behavior 1, 2
- Syphilis: Screen if engaging in high-risk sexual behavior 1
- Trichomoniasis: Not recommended for routine screening unless high-risk factors present 1
For Males (16 years old)
- Chlamydia: Annual screening recommended for sexually active males, particularly in high-prevalence settings (≥2% prevalence) 1, 2
- Gonorrhea: Annual screening recommended for sexually active males, particularly in high-prevalence settings (≥2% prevalence) 1, 2
- HIV: Screen if engaging in high-risk sexual behavior 1, 2
- Syphilis: Screen if engaging in high-risk sexual behavior 1
Special Considerations for MSM (Men who have Sex with Men)
- Screen for pharyngeal, rectal, and urethral gonorrhea annually if engaging in receptive oral/anal or insertive intercourse 1
- Screen for chlamydia at relevant anatomic sites based on sexual practices 1, 2
- More frequent screening (every 3-6 months) if high-risk behaviors present 1, 2
- Annual syphilis screening, or every 3-6 months if high-risk 1
Testing Methods
- Urine NAAT (nucleic acid amplification test) is preferred for chlamydia and gonorrhea screening 2
- Pharyngeal testing for those engaging in receptive oral sex 2
- Rectal testing for those engaging in receptive anal intercourse 2
- Serum testing for HIV and syphilis screening 2
Rescreening Recommendations
- Rescreen all adolescents diagnosed with chlamydia or gonorrhea 3 months after treatment, regardless of whether partners were treated 1, 2
- If 3-month rescreening isn't possible, retest at next healthcare visit within 12 months 1
Risk Factors Requiring More Intensive Screening
- Multiple or anonymous sexual partners
- Inconsistent condom use
- Sex under the influence of drugs/alcohol
- History of previous STIs
- Sex in exchange for money or drugs
- Injection drug use
- MSM status with multiple partners
Common Pitfalls to Avoid
- Missing asymptomatic infections: Most STIs in adolescents are asymptomatic but can lead to serious long-term complications if untreated 3
- Failing to rescreen after treatment: High reinfection rates make the 3-month post-treatment test critical 1, 2
- Overlooking anatomic site-specific testing: Testing should be guided by sexual practices (oral, anal, vaginal) 1, 2
- Neglecting to screen males: While female screening is emphasized in guidelines, sexually active adolescent males also require appropriate screening 1
- Forgetting to consider local prevalence: Local STI prevalence rates should influence screening decisions, especially for males 1
Additional Preventive Measures
- Verify hepatitis B vaccination status and offer if not previously completed 2
- Consider hepatitis C screening if additional risk factors present 2
- HPV vaccination is recommended through age 21 for males and age 26 for females 2
Implementing these evidence-based screening recommendations can significantly reduce STI-related morbidity in this vulnerable age group.