What birth control options are recommended for a 38-year-old non-smoking female?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Birth Control Options for a 38-Year-Old Non-Smoking Female

For a 38-year-old non-smoking female without medical contraindications, Long-Acting Reversible Contraceptives (LARCs) such as IUDs and implants are the most recommended birth control options due to their superior effectiveness (<1% failure rate) and convenience. 1

Contraceptive Options by Effectiveness

First-Line Options: Long-Acting Reversible Contraceptives (LARCs)

  • Levonorgestrel IUD (LNG-IUD): 0.1-0.2% typical failure rate 1
  • Copper T 380A IUD (Cu-IUD): 0.8% typical failure rate 1
  • Contraceptive Implant: 0.05% typical failure rate 1

Second-Line Options:

  • Injectable contraception (DMPA): 0.3-6% typical failure rate 1
  • Combined hormonal contraceptives (pills, patch, ring): 5-9% typical failure rate 1
  • Progestin-only pills: 5-9% typical failure rate 1

Key Considerations for a 38-Year-Old Woman

Safety Profile

  • As a non-smoker at age 38, the patient falls into Category 1 according to the U.S. Medical Eligibility Criteria, indicating no restrictions for any contraceptive method 1
  • For women approaching 40, the benefits of low-dose oral contraceptives outweigh potential risks when they are non-smokers 2
  • The absolute cardiovascular risk of hormonal contraceptives is very low in non-smokers without other risk factors 1

Effectiveness

  • LARCs provide the highest effectiveness rates (<1% failure) with no daily compliance required 1
  • Combined oral contraceptives have typical failure rates of 4-7% per year 3
  • The Pearl index for low-dose ethinylestradiol/levonorgestrel (20 μg/100 μg) is 0.88 4

Additional Benefits

  • Hormonal IUDs and COCs: Can help manage heavy menstrual bleeding and dysmenorrhea 1
  • COCs: Provide benefits beyond contraception, including decreased menstrual cramping, reduced blood loss, and improvement in acne 1
  • Extended or continuous COC cycles: May benefit women with anemia, severe dysmenorrhea, or endometriosis 1

Important Cautions

  • If selecting COCs, use formulations with the lowest effective dose of estrogen and progestogen 5
  • Pills containing levonorgestrel or norethisterone with ≤35 μg ethinylestradiol are considered first-line for COCs 5
  • Breakthrough bleeding is a common reason for discontinuation of low-dose oral contraceptives 6
  • No contraceptive method except condoms provides protection against STIs 1

Management Algorithm

  1. Assess for contraindications:

    • Even as a non-smoker, evaluate for history of DVT/PE, migraines with aura, uncontrolled hypertension, liver disease, or undiagnosed uterine bleeding
  2. Discuss preferences and priorities:

    • Effectiveness requirements
    • Desire for non-hormonal options
    • Need for cycle control or management of heavy bleeding
    • Frequency of administration preference
  3. Recommend optimal method based on effectiveness hierarchy:

    • If maximum effectiveness is priority: LARCs (IUD or implant)
    • If hormonal benefits needed: Hormonal IUD or low-dose COCs
    • If non-hormonal preferred: Copper IUD
  4. For COC users, provide guidance on missed pills:

    • If one pill is late (<24 hours): Take as soon as possible and continue normal schedule 7
    • If one pill is missed (24-48 hours): Take missed pill immediately, use backup method for 7 days 7
    • If two or more pills are missed (≥48 hours): Take most recent missed pill, use backup method, and consider emergency contraception if in first week 7
  5. Follow-up plan:

    • For LARC users: Check for proper placement after insertion
    • For COC users: Monitor for side effects and adherence

Remember that while hormonal contraceptives carry a small increased risk of venous thrombosis (7-10 events per 10,000 women-years compared to 2-10 events per 10,000 women-years with no hormonal method), this risk is still lower than that associated with pregnancy 3.

References

Guideline

Contraceptive Options for Women

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Choosing a combined oral contraceptive pill.

Australian prescriber, 2015

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.