Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 31, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Pain in Left Shoulder from Lifting

Single Most Likely Diagnosis

  • Rotator Cuff Strain: This is the most common cause of shoulder pain after lifting, due to the strain on the muscles and tendons of the rotator cuff.

Other Likely Diagnoses

  • Shoulder Impingement: The lifting motion can cause the shoulder blade to impinge on the rotator cuff, leading to pain and inflammation.
  • Bursitis: Inflammation of the bursae in the shoulder joint can occur due to repetitive motion or direct trauma from lifting.
  • Muscle Strain: Strain of the surrounding muscles, such as the deltoid or trapezius, can also cause shoulder pain after lifting.

Do Not Miss Diagnoses

  • Heart Attack (Myocardial Infarction): Although less common, shoulder pain can be a referred symptom of a heart attack, especially if the pain is radiating to the arm or jaw.
  • Pulmonary Embolism: Sudden onset of shoulder pain, especially if accompanied by shortness of breath or chest pain, could be a sign of a pulmonary embolism.
  • Thoracic Outlet Syndrome: Compression of the nerves or blood vessels in the thoracic outlet can cause shoulder pain, numbness, or tingling.

Rare Diagnoses

  • Osteonecrosis: Avascular necrosis of the humeral head can cause shoulder pain, although it is less common and usually associated with other risk factors such as steroid use or trauma.
  • Tumor: A tumor in the shoulder region, such as a bone or soft tissue tumor, can cause pain and should be considered in the differential diagnosis, although it is rare.
  • Infection: Septic arthritis or osteomyelitis of the shoulder joint can cause pain and fever, although it is uncommon and usually associated with other symptoms such as redness, swelling, or warmth.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.