Emergency Management of Severe Hypoglycemia in Type 2 Diabetes
For a blood glucose of 46 mg/dL in a type 2 diabetic patient, immediate treatment with 15-20g of fast-acting carbohydrates is required, followed by reassessment in 15 minutes and administration of additional glucose if levels remain below 70 mg/dL. 1, 2
Immediate Management Algorithm
Assess consciousness and ability to swallow safely:
Recheck blood glucose after 15 minutes:
- If still <70 mg/dL: Repeat glucose administration
- If ≥70 mg/dL but <3.9 mmol/L: Provide a substantial meal or snack containing complex carbohydrates and protein 1
For severe persistent hypoglycemia (still <54 mg/dL after initial treatment):
Recommended Sources of Fast-Acting Carbohydrates
- Preferred option: Pure glucose (glucose tablets) 1
- Alternative options:
Important: Protein-rich carbohydrate sources should NOT be used for treating hypoglycemia as they may increase insulin response without raising blood glucose adequately 1
Post-Emergency Management
After stabilizing blood glucose levels:
Identify the cause of hypoglycemia:
- Excessive insulin dose
- Missed or delayed meals
- Increased physical activity
- Alcohol consumption
- Medication interactions 3
Adjust diabetes management:
Provide patient education:
- Recognition of hypoglycemia symptoms
- Proper use of glucose monitoring
- Carrying emergency glucose sources at all times
- Importance of medical alert identification 2
Special Considerations
- Elderly patients are at higher risk for severe hypoglycemia and may have reduced ability to recognize symptoms 2
- Patients with recurrent hypoglycemia may develop hypoglycemia unawareness, making recognition of early warning signs difficult 3
- Patients on beta-blockers may have blunted symptoms of hypoglycemia 3
- Patients with renal or hepatic impairment may have altered glucose metabolism, increasing hypoglycemia risk 2
Follow-up Recommendations
- Schedule follow-up within 1-2 weeks to assess effectiveness of interventions 2
- Review blood glucose logs with particular attention to overnight readings 2
- Consider referral to diabetes education program for comprehensive management strategies 2
- For patients with frequent episodes of hypoglycemia, consider relaxing glycemic targets (A1C <8.0% rather than stricter goals) 2