Differential Diagnosis for Burning Sensation Outer Mouth
- Single most likely diagnosis
- Angular cheilitis: This condition is characterized by inflammation of the corners of the mouth, often causing a burning sensation, redness, and cracking. It is commonly associated with vitamin deficiencies, fungal infections, or mechanical factors like drooling or poorly fitting dentures.
- Other Likely diagnoses
- Dry mouth (xerostomia): A reduction in saliva production can lead to a burning sensation in the mouth, including the outer areas. This can be due to various factors such as medication side effects, autoimmune diseases like Sjögren's syndrome, or radiation therapy.
- Oral lichen planus: An autoimmune condition that can cause lesions and a burning sensation in the mouth, including the outer mucosa.
- Denture-related irritation: Ill-fitting dentures or allergic reactions to denture materials can cause irritation and a burning sensation on the outer mouth.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Oral cancer: Although less common, a burning sensation in a specific area of the outer mouth could be a symptom of oral cancer, particularly if accompanied by other signs like ulcers, bleeding, or a lump.
- Infections (bacterial, viral, or fungal): Certain infections, such as herpes simplex virus or bacterial infections, can cause severe burning sensations and should be promptly treated to prevent complications.
- Rare diagnoses
- Burning mouth syndrome (BMS): A chronic condition characterized by a burning sensation in the mouth without an identifiable cause. It's more common in post-menopausal women and can be challenging to diagnose and treat.
- Nutritional deficiencies (e.g., vitamin B12, iron, or zinc deficiency): These deficiencies can cause a range of oral symptoms, including a burning sensation, although they are less directly associated with the outer mouth compared to other areas.