Treatment of Tenosynovitis
The treatment of tenosynovitis should begin with NSAIDs as first-line therapy, followed by corticosteroid injections if symptoms persist, and surgical intervention only after 3-6 months of failed conservative management. 1
First-Line Treatment
Medications
- NSAIDs: Recommended as first-line treatment for tendon pain 1, 2
- Naproxen is FDA-approved specifically for tenosynovitis 2
- Recommended dosage: 500mg initially, followed by 500mg every 12 hours or 250mg every 6-8 hours as needed 2
- Initial total daily dose should not exceed 1250mg, with subsequent daily doses not exceeding 1000mg 2
- Use the lowest effective dose for the shortest duration to minimize side effects 2
Conservative Measures (RICE Protocol)
- Rest: Avoid activities that cause pain
- Ice: Apply for 15-20 minutes every 2-3 hours
- Compression: Use elastic bandage to reduce swelling
- Elevation: Keep affected limb elevated when possible 1
Second-Line Treatment
Corticosteroid Injections
- Effective for short-term pain control when NSAIDs fail 1
- Limitations:
- Limited to 2-3 injections with 4-6 weeks between injections
- Does not change long-term outcomes 1
- Success rate: Approximately 90% of cases respond to either single (58%) or multiple (33%) injections 3, 4
- Potential side effects include pain at injection site, stiffness, ecchymosis, or subcutaneous fat atrophy, but these are typically self-limited 3
Rehabilitation Approach
The American Physical Therapy Association recommends a phased rehabilitation approach 1:
Initial Phase (0-4 weeks):
- Focus on pain control
- Protected range of motion exercises
Intermediate Phase (4-8 weeks):
- Progressive strengthening exercises
Advanced Phase (8-12 weeks):
- Sport-specific or occupation-specific training
Imaging and Diagnosis
- Initial imaging: Plain radiographs (X-rays) if symptoms persist beyond 4-6 weeks 1
- Advanced imaging: If symptoms persist despite conservative management for 6-8 weeks:
Surgical Intervention
Consider surgical referral when:
- Symptoms persist despite 3-6 months of well-managed conservative treatment
- Significant functional limitations impact quality of life
- Recurrent episodes despite appropriate conservative management 1, 5
Surgical options may include tenosynovectomy, which can provide successful long-term relief from synovitis and prevent tendon ruptures 5
Special Considerations
Elderly Patients
- Consider lower doses of NSAIDs
- Use the lowest effective dose as prudent practice 2
Patients with Renal Impairment
- Naproxen-containing products are not recommended for patients with moderate to severe renal impairment (creatinine clearance <30 mL/min) 2
Rheumatoid Arthritis
- Early rheumatology referral if multiple joints are involved or systemic symptoms are present 1
- Tenosynovitis in rheumatoid arthritis may require more aggressive management to prevent tendon ruptures 5
Common Pitfalls to Avoid
- Delayed diagnosis: Tenosynovitis can lead to tendon rupture if left untreated, particularly in inflammatory conditions like rheumatoid arthritis
- Overuse of corticosteroid injections: Limit to 2-3 injections with 4-6 weeks between injections to prevent tendon weakening
- Inadequate rest: Continuing activities that exacerbate symptoms can prolong recovery
- Missing underlying causes: Some cases of tenosynovitis may be due to infections or systemic conditions like syphilis that require specific treatment 6
By following this treatment algorithm, most cases of tenosynovitis can be effectively managed without the need for surgical intervention.