Treatment of Tenosynovitis
The first-line treatment for tenosynovitis is NSAIDs, with naproxen specifically indicated for the relief of signs and symptoms of tendonitis, followed by corticosteroid injections if symptoms persist. 1, 2
Initial Management
First-Line Treatments
NSAIDs:
- Recommended as first-line pharmacological treatment 1
- Naproxen is FDA-approved specifically for tendonitis 2
- Initial dose: 500mg followed by 500mg every 12 hours or 250mg every 6-8 hours
- Maximum initial daily dose: 1250mg, then no more than 1000mg daily thereafter 2
- Use the lowest effective dose for the shortest duration to minimize side effects 2
RICE Protocol:
- Rest: Avoid activities that exacerbate pain
- Ice: Apply for 15-20 minutes every 2-3 hours
- Compression: Use elastic bandage to reduce swelling
- Elevation: Keep affected area elevated when possible 1
Second-Line Treatment
- Corticosteroid Injections:
- Recommended for moderate to severe cases that don't respond to NSAIDs 1
- Limited to 2-3 injections with 4-6 weeks between injections 1
- Effective in up to 61% of cases after a single injection 1, 3
- Studies show approximately 90% of de Quervain's tenosynovitis cases can be effectively managed with either single (58%) or multiple (33%) corticosteroid injections 4
Rehabilitation Approach
Progressive Rehabilitation Protocol
Initial Phase (0-4 weeks):
Intermediate Phase (4-8 weeks):
- Progressive strengthening exercises
- Low-load strengthening exercises
- Pool-based exercises if appropriate 1
Advanced Phase (8-12 weeks):
- Sport-specific or occupation-specific training
- Gradual return to full activity 1
When to Consider Referral
Orthopedic/Surgical Consultation
- Pain persists despite 3-6 months of well-managed conservative treatment
- Significant functional limitations impacting quality of life
- Suspicion of more serious pathology 1
- Approximately 10-12% of cases may require surgical intervention when injections fail or early recurrence occurs 3, 4
Rheumatology Referral
- Multiple joints are involved
- Presence of systemic symptoms
- Suspicion of underlying rheumatological condition 1
Important Considerations and Pitfalls
Diagnostic Pitfalls: Tenosynovitis can be a manifestation of underlying conditions such as rheumatoid arthritis or even infectious diseases like syphilis 1, 6
Treatment Pitfalls:
- Overuse of corticosteroid injections can lead to tendon weakening or rupture
- Inadequate rest during initial treatment can prolong recovery
- Failure to identify and address underlying causes 1
Special Populations:
- Elderly patients may require dose adjustments for NSAIDs
- Patients with renal or hepatic impairment should use lower doses of NSAIDs
- Naproxen is not recommended for patients with moderate to severe renal impairment 2
Return to Activity Criteria:
- Complete resolution of pain during and after activity
- Full range of motion compared to uninjured side
- Strength symmetry >90% compared to uninjured side
- Successful completion of activity-specific functional tests 1
By following this structured approach to tenosynovitis management, most patients can achieve symptom relief and return to normal function without requiring surgical intervention.