What are the steps to order a Positron Emission Tomography (PET) Computed Tomography (CT) scan?

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Last updated: September 5, 2025View editorial policy

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How to Place an Order for PET/CT

To order a PET/CT scan, follow a standardized protocol that includes providing complete clinical information, specifying scan parameters, and ensuring proper patient preparation instructions are communicated to the patient.

Required Clinical Information

  • Patient demographics: Full name, date of birth, weight, and height (critical for SUV calculations) 1
  • Clinical diagnosis: Specific cancer type or suspected condition 1
  • Relevant clinical history: Known tumor sites, previous treatments, and comorbidities (especially diabetes and inflammatory conditions) 2, 1
  • Results of previous imaging studies: CT, MRI, previous PET/CT scans 2
  • Recent treatments: Timing of chemotherapy, radiation, or surgery 1
  • Laboratory values: Kidney function (if contrast is needed) 1

Scan Specifications to Include

  • Anatomical coverage required: 2, 1

    • Whole-body (skull vertex to feet)
    • Torso (skull base to mid-thighs)
    • Limited area (specific region of interest)
    • Brain imaging (if needed)
  • Type of CT scan needed: 2

    • Low-dose CT (for attenuation correction only)
    • Diagnostic CT with contrast (specify oral, IV, or both)
  • Special positioning requirements: 2, 1

    • Arms up or down
    • For head and neck tumors: consider two-step protocol with arms down for head/neck portion and arms up for body scan
    • For radiation therapy planning: specify treatment position and need for immobilization devices

Patient Preparation Instructions

  • Fasting requirements: Patient must fast for at least 4-6 hours prior to the scan 2, 1, 3
  • Hydration: Patient should drink 1L of water during the 2 hours before injection 1
  • Activity restrictions: Avoid strenuous exercise for at least 6 hours (preferably 24 hours) before the scan 1
  • Medications: List any medications that should be continued or discontinued 2
  • For diabetic patients: Special instructions for blood glucose management 1, 3
  • For claustrophobic patients: Note need for possible premedication 1

Common Pitfalls to Avoid

  • Inadequate clinical information leading to misinterpretation 1
  • Unclear anatomical coverage resulting in incomplete imaging 1
  • Overlooking renal function when contrast is needed 1
  • Not accounting for diabetes, which can significantly affect image quality 1
  • Failing to specify positioning requirements for radiation planning 2, 1

PET/CT Acquisition Protocols

Different acquisition strategies may be employed depending on clinical needs: 2

  1. Strategy 1 (Basic Protocol):

    • CT topogram/scout scan
    • Low-dose CT scan
    • PET acquisition
  2. Strategy 2 (With Diagnostic CT):

    • Option A: Basic protocol followed by contrast-enhanced diagnostic CT
    • Option B: Contrast-enhanced diagnostic CT first, then low-dose CT and PET with appropriate delay
  3. Strategy 3 (Low-dose CT only):

    • CT topogram followed by low-dose CT and PET acquisition
  4. Strategy 4 (Full Diagnostic Protocol):

    • CT topogram
    • Deep-inspiration thoracic CT scan (if needed)
    • Whole-body diagnostic CT scan
    • PET acquisition

By following these guidelines when placing a PET/CT order, you'll ensure that the imaging facility has all necessary information to perform an optimal study tailored to the patient's specific clinical needs.

References

Guideline

PET/CT Scan Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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