Ventilator E-Sens and I-Sens Settings Scale
E-sens (expiratory sensitivity) and I-sens (inspiratory sensitivity) are not expressed on a scale from 1-6, but rather use different measurement units depending on the ventilator mode and manufacturer.
Understanding Ventilator Sensitivity Settings
I-Sens (Inspiratory Sensitivity)
- I-sens is typically measured in:
- Flow trigger: L/min (liters per minute)
- Pressure trigger: cmH₂O (centimeters of water)
- The American Thoracic Society recommends adjusting I-sens to avoid auto-triggering while minimizing work of breathing 1
- Lower numerical values indicate higher sensitivity (less patient effort needed)
- Higher numerical values indicate lower sensitivity (more patient effort needed)
E-Sens (Expiratory Sensitivity)
- E-sens is typically expressed as a percentage (%) of peak inspiratory flow
- Common settings range from 25-40% of peak flow 1
- Controls the transition from inspiration to expiration
- Lower percentages (25-30%) are recommended for patients with obstructive disease 2
- Higher percentages (35-40%) are recommended for patients with restrictive disease 2
Clinical Implications and Settings
For I-Sens:
- Starting with a default setting and adjusting based on patient response is recommended 1
- If auto-triggering occurs: decrease sensitivity (increase numerical value)
- If increased work of breathing: increase sensitivity (decrease numerical value)
For E-Sens:
- The ERS/ATS Task Force on Standards recommends starting with E-sens at approximately 25-30% of peak inspiratory flow 2, 1
- For patients with obstructive airways disease: use shorter inspiratory time (approximately 30% IPAP time) to allow adequate expiration time 2
- For patients with restrictive disease: use longer inspiratory time (approximately 40% IPAP time) 2
Practical Application
- When setting up non-invasive positive pressure ventilation (NPPV), the inspiratory time is calculated based on respiratory rate and I:E ratio 2
- The relationship between respiratory rate, cycle time, and inspiratory/expiratory time follows specific formulas:
- Cycle time = 60 / respiratory rate
- Inspiratory time = %IPAP time × cycle time
- I:E ratio = inspiratory time / expiratory time 2
Common Pitfalls to Avoid
- Mistaking sensitivity settings for a universal 1-6 scale
- Not accounting for different ventilator manufacturers using different units and scales
- Setting I-sens too sensitive, causing auto-triggering from cardiac oscillations or circuit leaks
- Setting I-sens too insensitive, increasing patient work of breathing
- Not adjusting E-sens based on underlying pathophysiology (obstructive vs. restrictive disease)
The proper adjustment of these settings is essential for optimizing patient comfort, reducing work of breathing, and improving ventilation outcomes 1.