Are E sens (expiratory sensitivity) and I sens (inspiratory sensitivity) expressed on a scale from 1-6?

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Ventilator E-Sens and I-Sens Settings Scale

E-sens (expiratory sensitivity) and I-sens (inspiratory sensitivity) are not expressed on a scale from 1-6, but rather use different measurement units depending on the ventilator mode and manufacturer.

Understanding Ventilator Sensitivity Settings

I-Sens (Inspiratory Sensitivity)

  • I-sens is typically measured in:
    • Flow trigger: L/min (liters per minute)
    • Pressure trigger: cmH₂O (centimeters of water)
  • The American Thoracic Society recommends adjusting I-sens to avoid auto-triggering while minimizing work of breathing 1
  • Lower numerical values indicate higher sensitivity (less patient effort needed)
  • Higher numerical values indicate lower sensitivity (more patient effort needed)

E-Sens (Expiratory Sensitivity)

  • E-sens is typically expressed as a percentage (%) of peak inspiratory flow
  • Common settings range from 25-40% of peak flow 1
  • Controls the transition from inspiration to expiration
  • Lower percentages (25-30%) are recommended for patients with obstructive disease 2
  • Higher percentages (35-40%) are recommended for patients with restrictive disease 2

Clinical Implications and Settings

For I-Sens:

  • Starting with a default setting and adjusting based on patient response is recommended 1
  • If auto-triggering occurs: decrease sensitivity (increase numerical value)
  • If increased work of breathing: increase sensitivity (decrease numerical value)

For E-Sens:

  • The ERS/ATS Task Force on Standards recommends starting with E-sens at approximately 25-30% of peak inspiratory flow 2, 1
  • For patients with obstructive airways disease: use shorter inspiratory time (approximately 30% IPAP time) to allow adequate expiration time 2
  • For patients with restrictive disease: use longer inspiratory time (approximately 40% IPAP time) 2

Practical Application

  • When setting up non-invasive positive pressure ventilation (NPPV), the inspiratory time is calculated based on respiratory rate and I:E ratio 2
  • The relationship between respiratory rate, cycle time, and inspiratory/expiratory time follows specific formulas:
    • Cycle time = 60 / respiratory rate
    • Inspiratory time = %IPAP time × cycle time
    • I:E ratio = inspiratory time / expiratory time 2

Common Pitfalls to Avoid

  • Mistaking sensitivity settings for a universal 1-6 scale
  • Not accounting for different ventilator manufacturers using different units and scales
  • Setting I-sens too sensitive, causing auto-triggering from cardiac oscillations or circuit leaks
  • Setting I-sens too insensitive, increasing patient work of breathing
  • Not adjusting E-sens based on underlying pathophysiology (obstructive vs. restrictive disease)

The proper adjustment of these settings is essential for optimizing patient comfort, reducing work of breathing, and improving ventilation outcomes 1.

References

Guideline

Ventilator Trigger Settings

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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