Success Rates of Lumbar Spinal Fusion
Lumbar spinal fusion has variable success rates ranging from 51-82% radiographically, with 65-78% of patients reporting clinical improvement, though radiographic fusion does not consistently correlate with clinical outcomes. 1
Radiographic Fusion Rates
Radiographic fusion rates vary considerably depending on the assessment method and follow-up duration:
- 51.5% at 12 months
- 61.4% at 24 months
- 66.7% at 36 months
- 77.8% at 48 months 1
In other studies:
- 82% fusion rate with instrumented posterolateral fusion 1
- 52% complete fusion, 24% questionable fusion, and 24% definitive pseudarthrosis in ALIF procedures 1
Clinical Success Rates
Clinical success rates generally range from 65-78%, though with significant variability:
- 65% clinical improvement based on patient self-assessment 1
- 78% of patients reported "complete relief" or "a good deal of relief" in long-term ALIF studies 1
- 68% average satisfactory outcome rate across multiple studies (range 16-95%) 2
- 77% of patients achieved clinically significant improvement in back pain in a recent Canadian study 3
Correlation Between Radiographic Fusion and Clinical Outcomes
The evidence regarding correlation between radiographic fusion and clinical outcomes is mixed:
Evidence Supporting Correlation
- Patients with solid fusions showed significantly better outcomes on three of four subsections of the Dallas Pain Questionnaire compared to those without solid fusions 1
- 86% of patients with successful fusion had good/excellent outcomes versus 56% in those with pseudarthrosis 1
- 91% of patients with fusion had superior clinical results compared with 41% of patients with nonunion 1
Evidence Against Correlation
- Several studies show no statistically significant correlation between radiographic fusion and clinical outcomes 1
- In a long-term study (10 years), clinical outcomes could not be correlated with the presence of radiographic fusion 1
- No significant difference was found in ODI and VAS scores between patients with fusion and those with nonunion in some studies 1
Factors Affecting Success Rates
Patient Selection
- Patients with abnormal MRI findings and abnormal discography had a 75% success rate versus 50% in those with normal MRI findings 4
- Patients with spondylolisthesis tend to have better outcomes than those with degenerative disc disease alone 5
Patient Expectations
- Patients typically consider success to be a decrease in pain intensity to 3/10 or less, improvement in ODI of 20 or more, discontinuing opioid medications, and return to occupational activity 6
- Achieving these minimum acceptable outcomes strongly correlates with patient satisfaction 6
Complications
Common complications affecting success rates include:
- Pseudarthrosis (14%) 2
- Chronic pain at bone graft donor site (9%) 2
- Overall adverse event rate of 19% in recent studies 3
Clinical Pitfalls to Consider
Overreliance on radiographic fusion: Radiographic evidence of fusion does not guarantee clinical improvement. Assessment should focus on functional outcomes and pain reduction rather than imaging alone.
Patient selection: Careful selection of appropriate surgical candidates is critical. Patients with specific indications like spondylolisthesis, isolated disc resorption with degenerative facet joints, or intervertebral disc disease with instability benefit most from fusion 5.
Psychosocial factors: Patients with compensation claims, psychological distress, and other psychosocial stressors may report satisfaction despite not achieving objective improvement 6.
Assessment timing: Fusion rates increase over time, so early assessment may underestimate ultimate fusion success. Complete evaluation should occur at least 24 months post-surgery 1.
Assessment methods: Plain radiography alone is less reliable than CT or other advanced imaging techniques for determining fusion status 1.
In summary, while lumbar spinal fusion can provide significant clinical benefit for carefully selected patients, the relationship between radiographic fusion and clinical outcomes is complex. Success rates should be evaluated based on both objective measures and patient-reported outcomes.