Symptoms of Hemorrhage Within Hours of Onset
In a hemorrhagic event with onset a few hours ago, you should expect to see rapidly progressing neurological deficits, decreasing level of consciousness, headache, vomiting, and elevated blood pressure as the most concerning symptoms. 1
Key Clinical Manifestations of Recent Hemorrhage
Neurological Symptoms
- Rapidly worsening focal neurological deficits - weakness, numbness, vision changes, or speech disturbances that progressively worsen over minutes to hours 1
- Decreasing level of consciousness - ranging from confusion to somnolence to coma 1
- Seizures - may occur within hours of hemorrhage onset (seen in <10% of ischemic strokes but more common in hemorrhagic events) 1
- Gaze preference or eye movement abnormalities - may indicate expanding hematoma with mass effect 1
Systemic Symptoms
- Severe headache - often described as sudden and the "worst headache of life" 1
- Vomiting - particularly concerning when associated with headache 1
- Hypertension - systolic blood pressure >220 mmHg is suggestive of hemorrhage 1
- Neck stiffness - may indicate subarachnoid extension of hemorrhage 1
Time Course and Progression
The severity of symptoms in hemorrhagic events typically increases rapidly within the first few hours due to:
- Active bleeding - Hemorrhage can continue for hours after symptom onset 1
- Hematoma expansion - 28-38% of patients show significant hematoma expansion within the first 3 hours 1
- Mass effect development - causing increased intracranial pressure and potential herniation 1
- Secondary injury - from inflammation and edema surrounding the hemorrhage 1
Diagnostic Considerations
If hemorrhage is suspected based on clinical presentation:
- Immediate neuroimaging is essential - CT or MRI should be performed urgently to distinguish between ischemic and hemorrhagic stroke 1
- CT angiography may identify patients at risk for hematoma expansion 1
- Serial neurological assessments using standardized scales (NIHSS, GCS) are crucial to detect deterioration 2
Warning Signs of Severe Hemorrhage
Particularly concerning signs that indicate a large or expanding hemorrhage include:
- Rapid deterioration in neurological status within hours of symptom onset 1
- Development of extensor posturing 1
- Pupillary abnormalities (dilated, sluggish, or unequal pupils) 1
- Respiratory pattern changes 2
- Cushing's triad (hypertension, bradycardia, irregular respirations) in advanced cases
Clinical Pitfalls
- Absence of severe symptoms does not exclude hemorrhage - Small hemorrhages may present with subtle findings initially but can expand rapidly 3
- Anticoagulation status matters - Patients on anticoagulants may have more rapid progression and worse outcomes 1
- Location affects presentation - Cerebellar hemorrhages may present with ataxia, nausea, and vomiting rather than focal deficits 1
- Delayed deterioration - Some patients may have a lucid interval before sudden deterioration, particularly with epidural hematomas 3
The absence of severe symptoms a few hours after onset should not provide false reassurance. Progressive hemorrhagic injury occurs in approximately 42-50% of patients with traumatic brain injury, with most progression occurring within the first 6-8 hours 3. Vigilant monitoring and serial neurological examinations are essential even if initial symptoms appear mild.