Treatment for Wasp Stings
For wasp stings, remove the stinger quickly if present, clean the area with soap and water, apply ice to reduce swelling, and use over-the-counter pain medications and antihistamines for symptom relief; however, for systemic reactions or anaphylaxis, immediately administer intramuscular epinephrine as the first-line treatment. 1
Initial Assessment and Treatment
Local Reactions (Most Common)
- Remove stinger (if present) as quickly as possible - the method is less important than speed 1
- Clean the wound thoroughly with soap and water 1
- Apply ice or cold packs to the sting site with a thin barrier between ice and skin to reduce pain and swelling 1
- Symptom management:
- Over-the-counter pain medications (acetaminophen or NSAIDs like ibuprofen)
- Oral antihistamines for itching
- Topical corticosteroids for inflammation 1
Systemic Reactions and Anaphylaxis (Emergency)
- Administer epinephrine immediately via intramuscular injection into the anterolateral thigh:
- Secondary treatments (should never delay epinephrine):
- H1 antihistamines
- H2 antihistamines
- Corticosteroids 1
- Monitor patient for at least 4-6 hours after treatment for signs of delayed or biphasic reactions 1
Special Considerations
Large Local Reactions
- May affect up to 25% of the population 3
- Oral antihistamines and oral corticosteroids may help manage symptoms 1
- Generally have a low risk of progressing to systemic reactions 1
Risk Factors for Severe Reactions
- History of previous systemic reactions
- Underlying mastocytosis (found in 3-5% of patients with sting anaphylaxis) 3
- Cardiovascular disease (still should receive epinephrine as benefits outweigh risks) 1
Potential Complications
Prevention and Follow-up Care
Prevention Strategies
- Have known nests removed by professionals
- Avoid wearing bright colors or flowery prints
- Wear protective clothing (long pants, long sleeves, closed shoes) 1
Follow-up Recommendations
- Patients with history of systemic reactions should:
- Carry autoinjectable epinephrine
- Be educated on proper use and indications
- Be referred to an allergist-immunologist 1
- Consider venom immunotherapy (VIT) for patients with history of systemic reactions and specific IgE to venom allergens 1
Infection Prevention
- Consider preemptive antibiotic therapy (3-5 days) for patients who are:
- Immunocompromised
- Asplenic
- Have advanced liver disease
- Have moderate to severe injuries, especially to hand or face 1
- Update tetanus prophylaxis if vaccination is not current (within 10 years) 1
Common Pitfalls to Avoid
- Delaying epinephrine administration in anaphylaxis (most critical error)
- Failing to monitor patients after treatment (biphasic reactions can occur)
- Underestimating the potential severity of wasp stings (can be fatal in sensitive individuals)
- Not referring patients with systemic reactions to an allergist for long-term management