Management of Post-Concussion Headaches
For post-concussion headaches, acetaminophen (1000 mg) or ibuprofen (400 mg) should be used as first-line treatment, with careful monitoring for analgesic overuse that can lead to rebound headaches. 1, 2
Initial Assessment and Management
Acute Phase (First 48 Hours)
- Acetaminophen (1000 mg) should be used as first-line treatment in the immediate post-concussion period 1, 2
- Avoid NSAIDs like ibuprofen in the first 48 hours due to potential bleeding risk 2
- Monitor for severe or worsening headache, which may indicate intracranial complications requiring emergent neuroimaging 1
After 48 Hours
- Ibuprofen (400 mg) can be introduced if acetaminophen is ineffective 1, 2
- Alternating acetaminophen and ibuprofen may be more effective than either medication alone for reducing headache days and intensity 3
Warning Signs Requiring Urgent Evaluation
- Acutely worsening headache symptoms
- Severe headache with other risk factors
- Headache that interferes with sleep
- New neurological symptoms
These symptoms warrant consideration for emergent neuroimaging to evaluate for intracranial complications 1, 2
Preventing Medication Overuse Headache
Medication overuse is a significant concern in post-concussion headache management:
- Up to 70% of adolescents with chronic post-traumatic headaches meet criteria for medication overuse headache 4
- Provide clear counseling about limiting analgesic use to ≤15 days/month for simple analgesics 1, 2
- Avoid opioids completely due to high risk of dependency and rebound headaches 2
- Nearly 70% of patients experience headache improvement after discontinuing overused analgesics 4
Activity Management
- Initial relative rest for 24-48 hours, avoiding activities that exacerbate symptoms 2
- Gradual return to light aerobic exercise following the 24-48 hour rest period 2
- Progress through a 5-stage return to activity protocol:
- Symptom-limited activity
- Light aerobic exercise
- Sport-specific exercise
- Non-contact training drills
- Full-contact practice
Each stage should last a minimum of 24 hours, with return to the previous stage if symptoms recur 2
Treatment Based on Headache Pattern
Headache characteristics should guide treatment approach:
- Migraine-like headaches: Consider NSAIDs (after 48 hours) and potentially triptans for moderate-severe headaches if persistent 2, 5
- Tension-type headaches: Acetaminophen (1000 mg) or ibuprofen (400 mg) 1
- Cervicogenic headaches: Consider referral for physical therapy targeting the cervical spine 2
Management of Chronic Post-Concussion Headaches
For headaches persisting beyond 3 months:
- Refer for multidisciplinary evaluation and treatment 1, 2
- Consider vestibular rehabilitation for patients with vestibulo-oculomotor dysfunction 1, 2
- Address sleep disturbances that may exacerbate headaches 2, 6
- Implement a biopsychosocial approach including exercise, multifaceted rehabilitation, and psychosocial interventions 6
Common Pitfalls to Avoid
- Analgesic overuse: Limit use to prevent rebound headaches
- Premature return to high-risk activities: Increases risk of second-impact syndrome
- Opioid use: Avoid due to dependency risk and rebound headaches
- 3% hypertonic saline: Not recommended due to insufficient evidence 1
- Neglecting psychological factors: Anxiety and depression can worsen post-concussion symptoms 6
Remember that approximately 15-20% of concussion patients develop post-concussion syndrome, with most experiencing symptom resolution within 7-10 days, but about 10% may have symptoms persisting beyond 3 months 2.