Characteristics of Popliteal Artery Aneurysms
Popliteal artery aneurysms are often bilateral, occurring in approximately 50% of affected patients, and frequently result in limb ischemia due to their high rate of thromboembolic complications. 1
Epidemiology and Prevalence
- Popliteal aneurysms account for 70% of all peripheral aneurysms in the lower extremities 1
- Estimated incidence of 0.1% to 2.8% in the general population 1
- Predominantly affect men, with a strong male predominance 2, 1
- Popliteal aneurysms are MORE common than femoral aneurysms (not less common as suggested in option A) 2
Bilateral Occurrence
- Approximately 50% of popliteal aneurysms are bilateral 2, 1
- This bilateral nature is an important diagnostic clue when evaluating patients with acute limb ischemia
- The presence of a prominent popliteal pulse in the opposite leg can help identify the underlying etiology of acute ischemia 2
Gender Distribution
- Popliteal aneurysms predominantly affect men 1
- In one study, 59 out of 61 patients (97%) with popliteal aneurysms were men 3
- They are NOT more common in females (contradicting option C)
Complications and Limb Ischemia
- Popliteal aneurysms frequently result in limb-threatening ischemia 2, 1, 3
- Thrombosis occurs in approximately 39% of cases, most often in larger aneurysms 2
- Thrombosis of popliteal arterial aneurysms accounts for approximately 10% of acute arterial occlusions in elderly men 2
- Severe ischemia usually occurs because:
- Thrombosis happens suddenly without collateral enhancement
- The popliteal artery is the sole axial artery traversing the knee 2
- 36% of patients with observed popliteal aneurysms develop complications 1
- Cumulative incidence of ischemic complications reaches 70% during 5-10 years of follow-up 1
Natural History
- Asymptomatic popliteal aneurysms have a high rate of becoming symptomatic:
- 50% become symptomatic within 2 years of discovery
- 75% become symptomatic within 5 years 1
- The probability of developing complications increases with time to 74% within 5 years 4
- Growth rate is approximately 1.5 mm per year for aneurysms >2.0 cm and 0.7 mm per year for aneurysms <2.0 cm 1
Management Recommendations
- Surgical indications include:
- Annual ultrasound monitoring is recommended for asymptomatic aneurysms <2.0 cm 1
- In patients with acute ischemia and absent runoff, catheter-directed thrombolysis or mechanical thrombectomy should be considered 2, 1
Common Pitfalls
- Mistaking thrombosed popliteal aneurysm for an embolic event 2, 1
- Failing to screen for contralateral popliteal aneurysms and abdominal aortic aneurysms 1
- Delaying treatment of asymptomatic aneurysms ≥2.0 cm 1
- Ultrasound is the initial diagnostic test of choice for popliteal aneurysms 1
In conclusion, popliteal artery aneurysms are more common than femoral aneurysms, often bilateral, predominantly affect men, and frequently result in limb-threatening ischemia due to thromboembolism.