What is the diagnosis for a 44-year-old male with abdominal pain for two weeks, nocturnal awakening, normal bowel movements, and no fever?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 44-year-old Male with Abdominal Pain

Single Most Likely Diagnosis

  • Musculoskeletal pain: Given the duration of two weeks and the fact that it wakes him up at night, musculoskeletal pain is a strong consideration. This type of pain can be exacerbated by movement or pressure and can occur at night, disrupting sleep.

Other Likely Diagnoses

  • Gastroesophageal reflux disease (GERD): Although the patient has normal bowel movements, GERD can cause abdominal pain that worsens at night, especially if the patient lies down after eating.
  • Peptic ulcer disease: The pain from a peptic ulcer can be constant and may worsen at night, though it typically improves with eating or antacids.
  • Inflammatory bowel disease (IBD): Conditions like Crohn's disease or ulcerative colitis can cause chronic abdominal pain, though they are often associated with changes in bowel movements, which this patient does not have.

Do Not Miss Diagnoses

  • Appendicitis: Although the patient's symptoms do not perfectly align with classic appendicitis (e.g., no fever, normal bowel movements), atypical presentations can occur, especially in adults. Missing appendicitis can lead to severe consequences, including perforation.
  • Pancreatitis: Acute pancreatitis can cause severe abdominal pain that may radiate to the back and can occur at night. It's a condition that requires immediate medical attention.
  • Diverticulitis: Inflammation of a diverticulum in the colon can cause severe pain, usually on the lower left side, and can be a medical emergency if complications arise.

Rare Diagnoses

  • Intestinal obstruction: This is a condition where the intestine is partially or completely blocked, which can cause severe abdominal pain, though it's often accompanied by vomiting, constipation, or obstipation, which this patient does not exhibit.
  • Abdominal aortic aneurysm: A ruptured or leaking abdominal aortic aneurysm can cause severe, sudden-onset abdominal pain, which is a medical emergency. However, this condition is less common in a 44-year-old without significant risk factors.
  • Cancer: Various abdominal cancers (e.g., stomach, pancreatic, colon) can cause chronic abdominal pain. While these are less likely given the patient's age and lack of other symptoms, they cannot be entirely ruled out without further investigation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.