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Last updated: September 11, 2025View editorial policy

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Differential Diagnosis for Left Side Shooting Pain in Eye

  • Single most likely diagnosis
    • Migraine: Shooting pain in one eye can be a symptom of a migraine, especially if accompanied by other migraine symptoms like sensitivity to light, nausea, or aura.
  • Other Likely diagnoses
    • Cluster headache: These are severe headaches that occur in cycles or clusters, often causing pain on one side of the head or around one eye.
    • Trigeminal neuralgia: This condition affects the trigeminal nerve, which can cause intense, shooting pain in parts of the face, including the eye area.
    • Optic neuritis: Inflammation of the optic nerve can cause pain, especially with eye movement, and is often accompanied by vision loss.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Acute angle-closure glaucoma: A medical emergency that causes severe eye pain, often accompanied by blurred vision, redness, and nausea. Prompt treatment is necessary to prevent vision loss.
    • Temporal arteritis (Giant Cell Arteritis): Inflammation of the blood vessels can cause severe headaches, jaw pain, and vision problems, including shooting pain in the eye area. If untreated, it can lead to blindness.
  • Rare diagnoses
    • Ocular melanoma: Though rare, eye cancer can cause pain, especially if the tumor presses on or invades nearby structures.
    • Sphenoid sinusitis: Infection or inflammation of the sphenoid sinus can cause deep, severe pain behind or around the eyes due to its location near the optic nerves and other critical structures.
    • Cavernous sinus thrombosis: A rare but potentially life-threatening condition where a blood clot forms in the cavernous sinus, which can cause severe headache, eye pain, and other neurological symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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