What is the treatment for peroneal tendonitis?

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Treatment for Peroneal Tendonitis

The treatment for peroneal tendonitis should begin with conservative management including NSAIDs as first-line medication, physical therapy with eccentric strengthening exercises, and activity modification, progressing to corticosteroid injections if initial treatment fails, with surgery reserved for cases refractory to 3-6 months of conservative treatment. 1

Conservative Management (First-Line Treatment)

Medications

  • NSAIDs: Strongly recommended as first-line treatment for tendon pain
    • Ibuprofen 1.2g daily is considered the safest option
    • Can be increased to 2.4g daily if inadequate relief is achieved
    • Can be combined with paracetamol (up to 4g daily) for enhanced pain control 1

Physical Therapy

  • Active interventions are conditionally recommended over passive interventions 1
  • Recommended program includes:
    • Eccentric strengthening exercises
    • Proprioception training
    • Functional rehabilitation 1
    • Manual therapy techniques (including lateral calcaneal glide) 2

Bracing and Support

  • Bracing is preferable to taping due to practical usability and cost considerations 1
  • Immobilization may be necessary during acute phase 3

Activity Modification

  • Reduce activities that exacerbate symptoms
  • Avoid repetitive ankle movements that stress the peroneal tendons

Second-Line Treatment

Corticosteroid Injections

  • Ultrasound-guided peroneal tendon sheath corticosteroid injections can be considered if initial conservative measures fail 3
  • Benefits:
    • 36.8% of patients experience pain relief for more than 12 weeks
    • Safe with minimal complications (1.8% reported) 3
  • Caution:
    • May lead to long-term deterioration of tendon tissue
    • Increased risk of recurrence 1
    • Limit to 2-3 injections with 4-6 weeks between injections 1

Surgical Management

Indications for Surgical Consultation

  • Persistent pain despite 3-6 months of well-managed conservative treatment
  • Functional limitations significantly impacting quality of life
  • Progressive tendon degeneration evident on follow-up imaging 1

Surgical Options Based on Pathology

  • For tears involving <50% of the tendon: Primary repair and tubularization
  • For tears involving >50% of the tendon: Tenodesis 4
  • For cases with hindfoot varus: Consider valgus osteotomy 5

Post-Surgical Rehabilitation

  • Critical for optimal outcomes
  • Focus on proprioception, strength, coordination, and function 1
  • Average time to return to work: 2.5 months
  • Average time to return to sport: 8.5 months 5

Diagnostic Considerations

Imaging

  • MRI: Highly effective for diagnosing peroneal tendon pathology
    • 83.9% sensitivity for tendinopathy
    • 54.5% sensitivity for tendon tears 1
  • Ultrasound: 100% sensitivity and 90% accuracy for diagnosing peroneal tendon tears 1

Return to Activity Criteria

  • Complete resolution of pain during and after activity
  • Full range of motion compared to uninjured side
  • Strength symmetry >90% compared to uninjured side
  • Successful completion of sport-specific functional tests 1

Common Pitfalls and Caveats

  • Peroneal tendon disorders are frequently missed and should be considered in all patients with chronic lateral ankle pain 6, 4
  • Anatomic variants may predispose to peroneal tendon injuries and should be identified during diagnostic workup 6
  • Patients with lower functional demands may do well with conservative treatment, while those with higher demands may benefit from earlier surgical intervention if conservative measures fail 6
  • Pre-injection duration of symptoms is associated with post-injection duration of pain relief, with longer-standing symptoms potentially responding less favorably to injections 3

References

Guideline

Adhesive Capsulitis Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Operative treatment for peroneal tendon disorders.

The Journal of bone and joint surgery. American volume, 2008

Research

The surgical treatment of peroneal tendinopathy (excluding subluxations): a series of 17 patients.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, 2012

Research

High-resolution US and MR imaging of peroneal tendon injuries.

Radiographics : a review publication of the Radiological Society of North America, Inc, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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