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Last updated: September 12, 2025View editorial policy

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Differential Diagnosis for Cervical Adenitis

Single Most Likely Diagnosis

  • Streptococcal or Staphylococcal Infection: This is the most common cause of cervical adenitis, particularly in children. It is usually a result of a bacterial infection of the throat or skin that spreads to the lymph nodes in the neck.

Other Likely Diagnoses

  • Viral Upper Respiratory Infection: Viruses such as influenza, adenovirus, and enterovirus can cause cervical adenitis, often as part of a broader upper respiratory infection.
  • Tuberculosis (TB): Although less common in some regions, TB is a significant cause of cervical adenitis, especially in areas with high TB prevalence or in immunocompromised individuals.
  • Cat-Scratch Disease: Caused by Bartonella henselae, this infection is transmitted through cat scratches or bites and can lead to cervical adenitis.

Do Not Miss Diagnoses

  • Lymphoma: Both Hodgkin's and non-Hodgkin's lymphoma can present with cervical adenitis. Missing this diagnosis could lead to delayed treatment of a potentially life-threatening condition.
  • Metastatic Cancer: Cervical adenitis can be a sign of metastasis from various cancers, including head and neck cancers, lung cancer, and others. Early detection is crucial for treatment and prognosis.
  • Sarcoidosis: Although rare, sarcoidosis can cause cervical adenitis and is important to consider, especially in patients with other systemic symptoms or findings suggestive of sarcoidosis.

Rare Diagnoses

  • Toxoplasmosis: Typically seen in immunocompromised patients, toxoplasmosis can cause cervical adenitis.
  • Actinomycosis: A rare bacterial infection that can cause chronic cervical adenitis, often associated with dental procedures, oral surgery, or other forms of trauma to the mouth.
  • Brucellosis: A zoonotic infection that can cause cervical adenitis, among other symptoms, usually acquired through contact with infected animals or their products.
  • Histoplasmosis: A fungal infection that can cause cervical adenitis, particularly in individuals who have been exposed to bird or bat droppings.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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