Treatment of Cough in Breastfeeding Mothers
For breastfeeding mothers with cough, first-line treatment should be dextromethorphan-containing products for symptomatic relief, as they are considered compatible with breastfeeding and provide effective cough suppression. 1
First-Line Treatment Options
Non-Pharmacological Approaches
- Adequate hydration to thin secretions
- Honey (for symptomatic relief) - safe for the mother (avoid giving honey directly to infants under 1 year)
- Humidification of air
Safe Pharmacological Options
Dextromethorphan
- Recommended dosage: 30 mg every 6-8 hours, not exceeding 120 mg in 24 hours 1
- Considered safe during breastfeeding
- Minimal transfer to breast milk
Guaifenesin (expectorant)
- Useful for productive cough with thick mucus
- Compatible with breastfeeding
Glycerol-based cough syrups (e.g., Benylin, Robitussin)
- Provide symptomatic relief for dry coughs
- Low cost and favorable side effect profile 1
Second-Line Treatment Options
First-generation antihistamines (for nighttime symptoms)
- Can be useful for nocturnal cough
- Produce somnolence that can be beneficial for sleep 1
- Take immediately after breastfeeding to minimize infant exposure
Non-sedating antihistamines (for daytime symptoms)
- Use when alertness is needed 1
- Less likely to cause drowsiness
Inhaled ipratropium bromide
- Consider for post-infectious cough 2
- Minimal systemic absorption, making it safe during lactation
Special Considerations for Breastfeeding Mothers
Medication Administration Tips
- Take medications immediately after breastfeeding to minimize infant exposure 1, 3
- Use the lowest effective dose for the shortest duration 1
- Choose medications with short half-lives and high protein binding 4
Safe Analgesics (if needed for associated symptoms)
- Acetaminophen (Paracetamol) - considered safe during breastfeeding 5, 6
- Ibuprofen - short-acting NSAID preferred for breastfeeding mothers 5, 6
When to Seek Further Medical Evaluation
- Cough persisting beyond 1-2 weeks 1
- Presence of concerning symptoms:
- Hemoptysis (coughing up blood)
- Significant breathlessness
- Prolonged fever
- Worsening of pre-existing conditions 1
Medications to Avoid During Breastfeeding
Codeine and other opioid-containing cough suppressants
- Can cause infant sedation 3
- Risk of respiratory depression in infants
High-dose aspirin (>100 mg/day)
- Safer alternatives should be considered 6
Dipyrone
- Safer alternatives should be considered 6
Diagnostic Approach for Persistent Cough
If cough persists beyond 1-2 weeks, evaluate for underlying causes:
- Post-viral cough (3-8 weeks duration)
- Asthma
- Gastroesophageal reflux disease (GERD)
- Post-nasal drip/Upper airway cough syndrome 1
Influenza Considerations
If influenza is suspected:
- Breastfeeding should be encouraged even if the mother has influenza 2
- If unable to breastfeed directly, pump and feed expressed breast milk 2
- Oseltamivir (75 mg twice daily for 5 days) can be used if indicated, as it's compatible with breastfeeding 2
Remember that maintaining breastfeeding is important as it provides protective benefits against respiratory illnesses for the infant. Human milk from mothers contains immunological factors that help protect infants from infections 2.