What are the management options for intrauterine device (IUD) side effects?

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Last updated: September 13, 2025View editorial policy

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Management of Intrauterine Device (IUD) Side Effects

The management of IUD side effects should focus on identifying underlying causes, providing appropriate treatment, and considering alternative contraceptive methods when side effects remain unacceptable to the patient despite interventions. 1

Bleeding Irregularities

Irregular Bleeding with LNG-IUD

  • Initial approach:
    • Provide reassurance that unscheduled spotting or light bleeding is common during the first 3-6 months of LNG-IUD use and typically decreases with continued use 1
    • Approximately 50% of LNG-IUD users will experience amenorrhea or oligomenorrhea by 2 years of use 1
    • Heavy or prolonged bleeding is uncommon with LNG-IUD use

Irregular Bleeding with Copper IUD

  • The main side effect of copper IUDs is increased menstrual bleeding, which may continue even with long-term use 2
  • Bleeding and pain are the most common reasons for removal rates of 10% in the first year and up to 50% within 5 years 3

Management Algorithm for Bleeding Issues

  1. Rule out underlying conditions:

    • Check for IUD displacement
    • Screen for STIs
    • Exclude pregnancy
    • Evaluate for pathologic uterine conditions (polyps, fibroids) 1
  2. If underlying condition identified:

    • Treat the specific condition or refer for appropriate care 1
  3. If no underlying condition but bleeding persists:

    • Consider non-steroidal anti-inflammatory drugs (NSAIDs) for copper IUD-related menorrhagia 4
    • Consider iron supplementation if bleeding is heavy to prevent anemia 5
    • If bleeding remains unacceptable to the patient, counsel on alternative contraceptive methods 1

Amenorrhea with LNG-IUD

  • Requires no medical treatment - provide reassurance 1
  • If amenorrhea occurs abruptly, consider ruling out pregnancy if clinically indicated 1
  • If amenorrhea is unacceptable to the patient, discuss alternative contraceptive methods 1

Pain Management

Acute Pain (During Insertion)

  • Evidence supports the use of:
    • Cervical block
    • 10% lidocaine spray
    • 5% lidocaine-prilocaine cream 6
  • Despite common practice, ibuprofen is less effective than lidocaine-based analgesics for insertion pain 6

Ongoing Pain with IUD

  1. Rule out complications:

    • Check for IUD malposition
    • Evaluate for infection
    • Exclude pregnancy
  2. Management options:

    • NSAIDs for pain relief
    • If pain persists and is unacceptable, consider IUD removal and alternative contraceptive methods 1

Management of IUD-Related Infections (PID)

If PID is diagnosed in an IUD user:

  1. Treat according to CDC Sexually Transmitted Diseases Treatment Guidelines 1
  2. Provide comprehensive management including condom counseling 1
  3. The IUD does not need immediate removal if ongoing contraception is desired 1
  4. Reassess in 24-48 hours:
    • If clinical improvement occurs, continue antibiotics and maintain IUD
    • If no improvement, continue antibiotics and consider IUD removal 1
  5. If IUD removal is preferred, start antibiotics first before removing the IUD to reduce risk of bacterial spread 1

Management of IUD with Pregnancy

If pregnancy occurs with an IUD in place:

  1. Evaluate for possible ectopic pregnancy 1
  2. Advise the woman about increased risks of:
    • Spontaneous abortion (including potentially life-threatening septic abortion)
    • Preterm delivery 1
  3. If IUD strings are visible:
    • Remove the IUD by gently pulling on strings 1
    • Removal reduces risks but may not decrease to baseline pregnancy risk 1
  4. Advise to seek care promptly if experiencing heavy bleeding, cramping, pain, abnormal discharge, or fever 1

Special Considerations

Adolescents with Disabilities

  • LNG-IUD is recommended due to high efficacy, long duration, and favorable side effect profile 5
  • Set realistic expectations with caregivers that complete amenorrhea may be difficult to achieve 5
  • Consider iron supplementation if breakthrough bleeding is heavy 5

Common Pitfalls to Avoid

  1. Premature IUD removal:

    • Treatment outcomes generally don't differ between women with PID who retain the IUD versus those who have it removed, provided appropriate antibiotic treatment and close follow-up are implemented 1
  2. Inadequate counseling:

    • Failure to discuss expected bleeding patterns before insertion leads to unnecessary removals 1
    • Emphasize that bleeding irregularities are generally not harmful 1
  3. Overlooking underlying conditions:

    • Always consider IUD displacement, STIs, pregnancy, or uterine pathology when evaluating bleeding or pain 1
  4. Ineffective pain management:

    • Lidocaine 2% gel and most NSAIDs are ineffective for insertion pain 7
    • Consider more effective options like lidocaine formulations, tramadol, or naproxen for specific patient groups 7

By following this structured approach to managing IUD side effects, clinicians can help patients maintain this highly effective contraceptive method while minimizing discomfort and complications.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Intrauterine devices: an update.

American family physician, 2014

Research

Intrauterine devices and intrauterine systems.

Human reproduction update, 2008

Guideline

Menstrual Suppression in Adolescents with Disabilities

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Interventions for pain with intrauterine device insertion.

The Cochrane database of systematic reviews, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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