What is the maximum recommended dose of Adderall (amphetamine and dextroamphetamine)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

The maximum recommended dose of Adderall is 40 mg per day for adults with ADHD, though some specialists may prescribe up to 60 mg in divided doses for certain patients, as supported by the most recent and highest quality study 1. When considering the maximum dose of Adderall, it's essential to take into account individual factors such as body weight, metabolism, other medications, cardiovascular health, and history of substance use disorders.

  • The FDA-approved maximum daily dose for adults with ADHD is 40 mg, with some specialists prescribing up to 60 mg in divided doses for certain patients.
  • For narcolepsy, the maximum daily dose is typically 60 mg.
  • Children's dosing is weight-based and more conservative, with maximums of 30 mg for ages 6-12 and 40 mg for adolescents. The medication works by increasing norepinephrine and dopamine in the brain, improving focus and attention.
  • Dosing should start low and increase gradually under medical supervision, with regular monitoring of vital signs, weight, and side effects.
  • Patients should never exceed prescribed doses, as amphetamine toxicity can be dangerous and potentially fatal, as noted in studies on Adderall toxicity 2. It's crucial to prioritize the single most recent and highest quality study, which in this case is 1, to ensure the best possible outcome in terms of morbidity, mortality, and quality of life.
  • This study, published in 2018, examined the efficacy and safety of amphetamines for adults with ADHD and found that amphetamines reduced the severity of ADHD symptoms, but were associated with higher attrition due to adverse events.
  • The study's findings are consistent with the FDA-approved maximum daily dose and highlight the importance of careful dosing and monitoring to minimize the risk of adverse effects.

References

Research

Amphetamines for attention deficit hyperactivity disorder (ADHD) in adults.

The Cochrane database of systematic reviews, 2018

Research

Adderall® (amphetamine-dextroamphetamine) toxicity.

Topics in companion animal medicine, 2013

Related Questions

What is the maximum recommended dose of Adderall (amphetamine and dextroamphetamine) for adults with Attention Deficit Hyperactivity Disorder (ADHD)?
What is the typical starting dose of Adderall (amphetamine and dextroamphetamine) for adults with Attention Deficit Hyperactivity Disorder (ADHD)?
What is the recommended dosing and titration schedule for Adderall (amphetamine and dextroamphetamine) in children, adolescents, and adults?
What is the recommended dosing for Adderall (amphetamine/dextroamphetamine) IR?
What is the difference between amphetamine salts and dextroamphetamine for treating Attention Deficit Hyperactivity Disorder (ADHD) or narcolepsy in adults and children?
What is the next best step for an elderly patient with advanced dementia, congestive heart failure (CHF), and colon cancer (Ca) who experiences improved peripheral edema on Lasix (furosemide) 40mg orally twice daily, but develops impaired renal function when the dose is increased from 60mg orally once daily to 40mg orally twice daily?
Is Tretinoin (all-trans retinoic acid) effective for treating striae (stretch marks)?
What is the recommended duration of intravenous (IV) dexamethasone (a corticosteroid) therapy for spinal cord infarction?
What is the management of a 5.2 cm simple ovarian cyst in a 24-year-old female with an Intrauterine Device (IUD)?
What is the difference between crackles and rhonchi (rales)?
What is the management of a 4.9cm simple ovarian cyst in a 24-year-old female with an Intrauterine Device (IUD)?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.