Management Options for Degenerative Spondylosis
Lumbar fusion is recommended for patients with chronic low-back pain due to 1-2 level degenerative disc disease that is refractory to conservative treatment. 1
Initial Conservative Management
Conservative management should be the first-line approach for degenerative spondylosis:
Physical Therapy
- Spinal mobility exercises
- Core strengthening
- Posture correction
- Flexion strengthening exercises 2
Medication Management
- NSAIDs at maximum tolerated doses (with consideration of cardiovascular, gastrointestinal, and renal risks)
- Muscle relaxants for acute pain episodes
- Analgesics for pain control 2
Adjunctive Therapies
Activity Modification
- Correction of poor posture
- Elimination of stressful occupational requirements
- Avoidance of certain spine movements 3
Comprehensive Rehabilitation Program
For patients with chronic low-back pain due to degenerative spondylosis, a comprehensive rehabilitation program incorporating cognitive therapy is recommended as an alternative to surgery 1. This should include:
- Intensive physical therapy
- Pain management strategies
- Cognitive behavioral approaches to pain
- Self-management education
Surgical Management
Surgical intervention should be considered when conservative measures fail to provide adequate symptom relief:
Indications for Surgery
- Chronic low-back pain refractory to 6+ weeks of conservative treatment
- Pain due to 1-2 level degenerative disc disease without stenosis or spondylolisthesis
- Significant functional limitations 1
Surgical Options
Lumbar Fusion: Recommended for carefully selected patients with disabling low-back pain due to 1-2 level degenerative disease without stenosis or spondylolisthesis (Grade B recommendation) 1
Decompression with Fusion: For patients with degenerative spondylolisthesis with stenosis, decompression with fusion shows better outcomes than decompression alone 1
Minimally Invasive Surgery: Promising approach for degenerative spondylolisthesis, promoting early recovery and enhanced quality of life by reducing muscular damage and perioperative pain 4
Special Considerations
Degenerative Spondylolisthesis
- Prognosis is generally favorable with conservative management
- Patients with neurological symptoms (intermittent claudication, vesicorectal disorder) may experience neurological deterioration without surgery 2
- The preponderance of evidence favors fusion following decompression in patients with stenosis and spondylolisthesis, particularly in those requiring extensive decompression 1
Cervical Spondylosis
- Usually produces intermittent neck pain that responds to activity modification, neck immobilization, isometric exercises, and medication
- Surgical intervention should be considered for persistent pain or progressive neurologic deficit 5
- For cervical spondylotic myelopathy, neck immobilization can result in improvement in 30-50% of patients with minor neurologic findings 5
Monitoring and Follow-up
- Regular assessment of pain levels and functional status
- Radiographic monitoring generally not needed more frequently than once every 2 years 1
- Monitor for complications such as spinal fractures or advanced hip arthritis
Pitfalls and Caveats
Surgical Outcomes: While fusion procedures show good initial results, functional outcomes may decline with long-term follow-up, raising questions about how much surgical treatment affects the natural course of the disease 5
Pedicle Screw Fixation: Routine use of pedicle screw instrumentation does not necessarily improve functional outcomes in all patients; however, it may benefit those with kyphosis or excessive motion at the site of degenerative spondylolisthesis 1
Patient Selection: Careful patient selection is critical for surgical success, as not all patients with degenerative changes on imaging are appropriate surgical candidates
Conservative Treatment Duration: A minimum of 6 weeks of conservative management should be attempted before considering surgical interventions