What is the treatment for second-degree burns?

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Last updated: September 15, 2025View editorial policy

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Treatment of Second-Degree Burns

The recommended treatment for second-degree burns includes immediate cooling with cold tap water (15-25°C) for at least 15 minutes, followed by application of 1% silver sulfadiazine cream to a thickness of approximately 1/16 inch once to twice daily, and covering with sterile, non-adherent dressings. 1, 2

Initial Management

  1. Immediate cooling:

    • Cool the burn with cold (15-25°C) tap water until pain is relieved 1
    • Continue cooling for at least 15 minutes
    • NEVER apply ice directly to burns as this can worsen tissue damage
  2. Wound assessment:

    • Evaluate burn depth, extent (% total body surface area), and location
    • Burns to face, hands, feet, genitalia, or >10% TBSA in children or >20% TBSA in adults require immediate medical attention 1
  3. Decontamination:

    • Remove any contaminated clothing, jewelry, or material from affected areas 1
    • Leave burn blisters intact as this improves healing and reduces pain 1

Wound Care Protocol

Step 1: Wound Preparation

  • Clean and debride the wound under sterile conditions 1, 2
  • Protect intact blisters with loose sterile dressing to prevent accidental rupture 1

Step 2: Antimicrobial Application

  • Apply a thin layer (approximately 1/16 inch) of 1% silver sulfadiazine cream to the burn wound 1, 2
  • Silver sulfadiazine is specifically indicated as an adjunct for prevention and treatment of wound sepsis in second and third-degree burns 2
  • Ensure the burn areas are covered with silver sulfadiazine cream at all times 2

Step 3: Dressing Application

  • Cover the burn with a sterile, non-adherent dressing applied loosely 1
  • While dressings are not always required with silver sulfadiazine, they may be used based on individual patient needs 2
  • Reapply silver sulfadiazine immediately after hydrotherapy or when removed by patient activity 2

Pain Management

  • Implement a multimodal approach to pain management:
    • First-line: Acetaminophen 1g every 4-6 hours 1
    • Second-line: Add NSAIDs for inflammatory pain 1
    • Third-line: Short-acting opioids and ketamine for severe pain 1
  • Consider non-pharmacological techniques such as virtual reality or hypnosis to reduce pain intensity and anxiety 1

Ongoing Care

  • Continue treatment with silver sulfadiazine until satisfactory healing has occurred or until the burn site is ready for grafting 2
  • Begin early range of motion exercises to prevent contractures 1
  • Monitor for signs of infection (increased pain, redness, swelling, purulent discharge, fever) 1
  • Perform regular wound assessment to detect early signs of infection and monitor healing progress 1

Special Considerations

  • For extensive burns, initiate fluid resuscitation with careful monitoring of fluid balance 1
  • Start nutritional support within 12 hours after burn injury, preferably via oral or enteral route 1
  • Monitor for signs of compartment syndrome in extremity injuries (5 P's: pain, pallor, paresthesia, pulselessness, paralysis) 1

Common Pitfalls to Avoid

  • Applying ice directly to burns (causes vasoconstriction and can worsen tissue damage)
  • Breaking intact blisters (increases infection risk and delays healing)
  • Inadequate pain management (can lead to increased anxiety and delayed healing)
  • Discontinuing antimicrobial treatment prematurely (may result in wound infection)
  • Applying silver sulfadiazine too thickly (wastes medication and doesn't improve outcomes)

The 2024 consensus on second-degree burn treatment emphasizes the importance of standardized approaches to burn management, including proper prehospital first aid, appropriate non-surgical and surgical treatments, and infection prevention 3, 4, 5. This comprehensive approach aims to improve outcomes and reduce complications in patients with second-degree burns.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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