What is the initial treatment for a 2nd (second) degree burn?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 7, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Initial Treatment for Second-Degree Burns

The initial treatment for second-degree burns should include immediate cooling with clean running water for 5-20 minutes, followed by appropriate wound dressing based on the burn size and characteristics. 1

Immediate First Aid Steps

  • Cool the burn immediately with clean running water for 5-20 minutes to limit burn depth progression and reduce pain 1
  • Monitor children for signs of hypothermia during cooling 1
  • If clean running water is not available, superficial burns with intact skin may be cooled with ice wrapped in cloth 1
  • Remove jewelry before swelling occurs to prevent constriction and vascular ischemia 1
  • Consider over-the-counter pain medications (acetaminophen or NSAIDs) for pain management 1

Wound Cleaning and Assessment

  • Clean the wound with tap water, isotonic saline, or an antiseptic solution 1
  • Perform wound care in a clean environment with appropriate pain control 1
  • Assess the burn for size, depth, and location to determine appropriate management 1
  • Note that burns involving face, hands, feet, genitals, or >10% body surface area (>5% in children) require specialized burn center treatment 1

Dressing Application

  • For small partial-thickness burns managed at home:

    • Apply petrolatum, petrolatum-based antibiotic ointment, honey, or aloe vera 1
    • Cover with a clean non-adherent dressing 1
  • For burns with intact skin or intact blisters:

    • Loosely cover with a clean cloth or non-adherent dry dressing 1
  • For larger burns requiring medical attention:

    • The type of dressing depends on the total burn surface area (TBSA), wound appearance, and patient's general condition 1
    • Antiseptic dressings may be appropriate for large or contaminated burns 1

Special Considerations

  • When applying dressings on limbs, prevent bandages from creating a tourniquet effect 1
  • Monitor distal perfusion in case of circular dressings 1
  • Ideally, dressings should be re-evaluated daily 1
  • Silver sulfadiazine is FDA-approved for prevention and treatment of wound sepsis in second and third-degree burns, but may be associated with prolonged healing if used long-term on superficial burns 2, 1
  • Topical antibiotics should not be used as first-line treatment but reserved for infected wounds only 1

When to Seek Medical Attention

  • Burns involving the face, hands, feet, or genitals 1
  • All full-thickness burns 1
  • Burns covering >10% body surface area in adults or >5% in children 1
  • Signs of inhalation injury (soot around nose/mouth, difficulty breathing, singed nasal hairs) 1
  • Burns with signs of infection 1

Pitfalls to Avoid

  • Do not use external cooling devices (e.g., Water-Jel dressings) for prolonged periods due to risk of hypothermia 1
  • Do not delay other resuscitation interventions for dressing application in severe burns 1
  • Avoid routine antibiotic prophylaxis for burn patients unless infection is present 1
  • Do not apply silver sulfadiazine for extended periods on superficial burns as it may delay healing 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.