Cancer Risk Assessment from Medical Images
Medical images themselves do not pose a cancer risk when used appropriately for diagnostic purposes. 1
Understanding Imaging and Radiation Risk
Medical imaging is a crucial diagnostic tool that helps detect diseases early, including cancer. However, there are often concerns about potential risks associated with certain types of imaging.
Types of Medical Imaging and Their Risk Profiles
- Non-radiation imaging modalities (MRI, ultrasound) have no known cancer risk
- Radiation-based imaging (X-rays, CT scans) involve ionizing radiation exposure:
- The risk from a single diagnostic imaging study is extremely small
- Radiation doses from most diagnostic procedures remain well below thresholds associated with measurable cancer risk 1
Radiation Risk in Context
According to the Oncologically Relevant Findings Reporting and Data System (ONCO-RADS) guidelines:
- Exposure <50 mGy has minimal risk (typical for most diagnostic imaging)
- Exposure >50 mGy is associated with a doubled relative risk of childhood cancer death, but this translates to only 1.1 to 3 additional cases per 1000 children 1
- Exposure >100 mGy may be associated with mental development effects
- Exposures >150-200 mGy increase malformation risks significantly 1
Risk-Benefit Assessment for Medical Imaging
The decision to perform any imaging study should be based on a clear risk-benefit assessment:
- Clinical necessity: Is the diagnostic information needed for proper treatment?
- Alternative options: Are non-radiation options available and appropriate?
- Patient factors: Age, pregnancy status, and previous radiation exposure
- Image optimization: Using the lowest radiation dose necessary for diagnosis
Special Considerations for Pregnant Women
For pregnant patients, the SFMU/SFAR/CNGOF guidelines state:
- Perform necessary imaging when clinically indicated, regardless of pregnancy status
- The risk/benefit balance should guide the decision to perform thoracic, abdominal, and/or pelvic CT scans 1
- Ultrasound and MRI are preferred when appropriate, but CT should not be avoided if it's the most appropriate test
Communicating Imaging Risks to Patients
Research shows significant variability in how imaging risks are communicated to patients:
- 65% of risks in patient decision aids are communicated using text format 1
- Visual formats (like icon arrays) enhance comprehension but are inconsistently used 1
- Patients want more information about imaging risks, particularly regarding radiation exposure 1
Best Practices for Risk Communication
- Use visual formats when possible to enhance comprehension
- Present balanced information about alternatives, benefits, and harms
- Provide context for radiation exposure (comparing to background radiation)
- Tailor information to the patient's health literacy level
Conclusion
Medical imaging is a valuable diagnostic tool with benefits that typically far outweigh potential risks when used appropriately. The cancer risk from diagnostic imaging is extremely small and should not deter patients from necessary diagnostic procedures. Healthcare providers should focus on appropriate use of imaging, optimization of radiation dose when applicable, and clear communication of risks and benefits to patients.