What is the significance of mild left hydroureteronephrosis secondary to a 2mm calculus at the left ureterovesical junction, as seen on a computed tomography (CT) scan of the abdomen and pelvis?

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Last updated: March 16, 2025View editorial policy

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Differential Diagnosis for Mild Left Hydroureteronephrosis

  • Single most likely diagnosis
    • Ureteral obstruction due to a 2mm kidney stone (urolithiasis) at the left ureterovesical junction: This is the most direct cause given the CT findings, as the stone's location at the ureterovesical junction can easily obstruct urine flow, leading to hydroureteronephrosis.
  • Other Likely diagnoses
    • Blood clot obstruction: A blood clot in the ureter could cause similar symptoms and findings, especially if there's an underlying condition like nephrolithiasis or urinary tract infection.
    • Ureteral stricture: Narrowing of the ureter, which could be due to various causes including previous surgery, infection, or inflammation, could also lead to obstruction and subsequent hydroureteronephrosis.
    • External compression (e.g., from a tumor or lymphadenopathy): Though less common, external compression of the ureter at the ureterovesical junction could cause obstruction.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Ureteral tumor: A tumor in the ureter, though rare, could cause obstruction and would have significant implications for treatment and prognosis.
    • Retroperitoneal fibrosis: A condition where fibrotic tissue forms in the retroperitoneum and can encase and obstruct the ureters, which could lead to severe consequences if not addressed.
    • Vascular obstruction (e.g., from an abdominal aortic aneurysm or other vascular abnormalities): Though rare, vascular causes of ureteral obstruction could have severe and immediate consequences.
  • Rare diagnoses
    • Congenital ureteral anomalies (e.g., ureteral duplication, ectopic ureter): These conditions could potentially cause obstruction, especially if associated with other anomalies like ureterocele.
    • Endometriosis involving the ureter: Rarely, endometriosis can cause external compression or invasion of the ureter, leading to obstruction.
    • Inflammatory or infectious processes (e.g., tuberculosis, schistosomiasis): In certain geographic areas or patient populations, these conditions could cause ureteral obstruction and subsequent hydroureteronephrosis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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