What is the management plan for a patient with normal cardiac structure and function, left ventricular ejection fraction (LVEF) of 59%, right ventricular ejection fraction (RVEF) of 64%, and trace mitral and tricuspid valve regurgitation?

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Management of Patient with Normal Cardiac Structure and Function

No specific intervention is required for a patient with normal cardiac structure and function, LVEF of 59%, RVEF of 64%, and trace mitral and tricuspid valve regurgitation, as these findings represent normal cardiac anatomy and physiology. 1

Understanding the Clinical Findings

The cardiac MRI findings in this case demonstrate:

  • Normal left and right atrial size
  • Normal left ventricular size and systolic function (LVEF 59%)
  • Normal right ventricular size and systolic function (RVEF 64%)
  • Trace mitral and tricuspid valve regurgitation (regurgitant volume <5 mL each)
  • No evidence of myocardial scarring
  • No significant interatrial shunt (Qp:Qs = 1)

Interpretation of Valve Regurgitation

According to established guidelines, trace or mild valve regurgitation is characterized by:

  • Regurgitant volume <30 mL/beat
  • Regurgitant fraction <30%
  • Effective regurgitant orifice (ERO) <0.10 cm² 1

The patient's regurgitant volume of <5 mL for both valves falls well below these thresholds, confirming physiologic (normal) regurgitation.

Management Approach

Clinical Follow-up

  • Routine cardiac evaluation every 1-2 years is sufficient 1
  • No need for frequent echocardiographic monitoring unless symptoms develop

Echocardiographic Surveillance

  • Repeat echocardiogram every 2-3 years if clinically stable 1
  • Earlier reassessment if symptoms develop

Medical Therapy

  • No specific cardiac medications are indicated for trace valve regurgitation with normal ventricular function 1
  • Vasodilator therapy is not indicated for normotensive asymptomatic patients with normal systolic left ventricular function 1

When to Consider Intervention

Intervention would only be considered if progression to significant valve disease occurs with:

  • Development of symptoms
  • Left ventricular dysfunction (LVEF ≤60%)
  • Left ventricular dilation (end-systolic dimension ≥40 mm) 2, 1

Prognosis

The prognosis for patients with trace mitral and tricuspid regurgitation and preserved ventricular function is excellent:

  • Most patients remain stable for many years
  • Progression to severe regurgitation is uncommon in the absence of other cardiac conditions 1

Preventive Measures

General cardiovascular health maintenance is recommended:

  • Blood pressure control
  • Maintaining healthy weight
  • Regular physical activity
  • Avoidance of smoking
  • Management of cholesterol levels 1

These findings represent normal cardiac anatomy and physiology, and no specific cardiac treatment is indicated at this time.

References

Guideline

Heart Valve Regurgitation Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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