Treatment of Cervicogenic Headache with Steroids
Steroids are not recommended as a first-line treatment for cervicogenic headaches, but they may be considered as an interventional option when other treatments fail.
Understanding Cervicogenic Headache
Cervicogenic headache (CGH) is defined as a headache secondary to disorders of the cervical spine and its elements including bony, disc, and/or soft tissue components 1. It affects approximately 4% of the general population and up to 20% of patients with chronic headaches 1. The pain typically originates from nociceptive sources in the upper cervical spine, including cervical muscles, disc spaces, facet joints, and nerve roots.
First-Line Treatment Approaches
Non-steroidal anti-inflammatory drugs (NSAIDs)
Non-pharmacological approaches
- Physical therapy interventions
- Regular exercise
- Maintaining regular sleep schedule
- Identification and avoidance of triggers
- Relaxation techniques
When to Consider Steroid Treatment
Steroid treatment may be considered when:
- First-line treatments have failed
- Patient has significant disability despite optimized acute therapy
- Conservative measures such as physical therapy have been unsuccessful
Steroid Treatment Options for Cervicogenic Headache
1. Cervical Epidural Steroid Injection (CESI)
- Can be used as both a diagnostic and therapeutic intervention 3
- Typically administered at C6-C7 or C7-T1 level
- Usually methylprednisolone 40 mg is injected into the epidural cervical space 4
- Short-term studies show marked clinical improvement in pain scores and reduced medication consumption in CGH patients 4
- However, evidence remains limited and controversial 3
2. Intraarticular Cervical Facet Steroid Injections
- Meta-analysis shows improvement in mean pain scores after treatment 5
- Overall effect size demonstrated a significant reduction in Visual Analog Scale scores (pooled mean difference: 3.299,95% CI: 2.045 to 4.552, P < 0.001) 5
- Should be considered when conservative treatments fail
Important Considerations and Limitations
Diagnostic challenges: CGH diagnosis is challenging due to heterogeneous definitions, overlapping symptoms with other headache disorders, lack of definitive radiological findings, and high prevalence of abnormal imaging findings in asymptomatic patients 1
Limited evidence: Scientific evidence for the effectiveness of steroid treatments in CGH is scarce 6
Individualized approach: Response to treatment varies significantly among patients 6
Medication overuse risk: To guard against medication-overuse headaches, limit acute treatments to no more than twice a week 1
Alternative interventions: Consider nerve blocks, facet joint injections, or other interventional procedures if steroid injections are ineffective 6
Monitoring and Follow-up
- Assess treatment efficacy after 2-3 months
- Monitor for potential steroid-related side effects
- Consider alternative approaches if inadequate response
While steroids administered by cervical epidural or intraarticular facet injection have been used in clinical practice for CGH, they should not be considered first-line therapy due to limited evidence of effectiveness and potential risks. They may be appropriate in selected patients who have failed conservative management.