From the FDA Drug Label
When using this product avoid contact with eyes do not exceed recommended dosage do not use for more than 7 days unless directed by a dentist or doctor Warnings Allergy Alert: do not use this product if you have a history of allergy to local anesthetics such as procaine, butacaine, benzocaine or other "caine" anesthetics When using this product avoid contact with eyes do not exceed recommended dosage do not use for more than 7 days unless directed by a dentist or doctor
The recommended dose and frequency of benzocaine administration is not explicitly stated in the provided drug labels.
- The labels advise not to exceed the recommended dosage, but the actual dosage is not specified.
- The labels also state not to use the product for more than 7 days unless directed by a dentist or doctor 1, 1. The FDA drug label does not answer the question.
From the Research
Benzocaine is typically used as a topical anesthetic in concentrations of 5-20%, with the standard adult dose being application of a thin layer to the affected area up to 3-4 times daily as needed for pain relief, as supported by the most recent study 2.
Key Considerations
- For oral applications such as toothaches or mouth sores, products containing 10-20% benzocaine can be applied directly to the painful area up to 4 times daily, with at least 1-2 hours between applications.
- For sore throats, benzocaine lozenges (typically 15 mg) can be dissolved in the mouth every 2 hours as needed, not exceeding 10 lozenges in 24 hours.
- Duration of use should generally be limited to 7 days unless directed otherwise by a healthcare provider.
- Benzocaine works by temporarily blocking nerve signals in the applied area, providing short-term pain relief.
Important Safety Information
- It's essential to use the minimum effective amount to avoid side effects, including rare but serious methemoglobinemia (a blood disorder that reduces oxygen delivery to tissues), which is more common with higher concentrations and excessive use, as highlighted in 2.
- Children under 2 years should not use benzocaine products, and those with certain medical conditions or taking specific medications should consult a healthcare provider before use.
Clinical Evidence
- A study published in 2017 2 demonstrated that pediatric exposure to topical benzocaine preparations can result in methemoglobinemia and other serious effects, emphasizing the need for cautious use and adherence to recommended dosages.
- Another study from 2002 3 showed that benzocaine is effective when used alone at a concentration of 20% and when combined at a dose of 15% with 1.7% amethocaine, but the optimal dosage and frequency should be determined based on individual patient needs and medical history.