From the FDA Drug Label
When using this product avoid contact with eyes do not exceed recommended dosage do not use for more than 7 days unless directed by a dentist or doctor The FDA drug label does not answer the question.
From the Research
Benzocaine and menthol are typically used together in over-the-counter products for temporary pain relief, with a recommended dose of 10-15 mg benzocaine and 2-10 mg menthol per lozenge or spray, used every 2 hours as needed, not exceeding 10 doses in 24 hours, as supported by the most recent study 1.
Key Considerations
- The combination of benzocaine and menthol works through different mechanisms, with benzocaine blocking nerve signals as a local anesthetic and menthol creating a cooling sensation that distracts from pain.
- For topical applications like creams or gels, products usually contain 5-20% benzocaine and 0.5-1% menthol, applied to the affected area 3-4 times daily.
- It's essential to use these products only for short periods (generally less than 7 days) and discontinue use if irritation develops.
- Children under 2 years should not use benzocaine products due to rare but serious risks of methemoglobinemia, a blood disorder, as highlighted in 2.
- Pregnant women should consult healthcare providers before use, and anyone with allergies to either ingredient should avoid these products.
Efficacy and Safety
- A recent study 1 demonstrated the efficacy and safety of a triple active sore throat lozenge containing benzocaine, showing a significant benefit over placebo in the treatment of acute pharyngitis.
- Another study 3 compared the efficacy of 2% lignocaine and 20% benzocaine gels in reducing pain during administration of local anesthesia, finding that 20% benzocaine showed better results than 2% lignocaine in reducing needle insertion pain.
Important Warnings
- Benzocaine products should be used with caution, especially in children and pregnant women, due to the risk of methemoglobinemia and other potential side effects.
- Patients should be advised to follow the recommended dosage and frequency of use, and to discontinue use if any adverse effects occur.