Recommended Methods for Assessing Confusion in Clinical Settings
The Confusion Assessment Method (CAM) and the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) are the most valid and reliable tools for assessing confusion and delirium in clinical settings. 1
Primary Assessment Tools
Confusion Assessment Method (CAM)
The CAM is the gold standard tool for delirium assessment in most clinical settings and can be completed in less than 5 minutes. It evaluates four key diagnostic features:
- Acute onset and fluctuating course
- Inattention
- Disorganized thinking
- Altered level of consciousness
For a positive delirium diagnosis, both criteria 1 and 2 must be present, along with either criterion 3 or 4 2. The CAM has demonstrated:
- Sensitivity: 82%
- Specificity: 99% 3
CAM-ICU
For mechanically ventilated or critically ill patients, the CAM-ICU is specifically designed to assess delirium in ICU settings, with:
- Sensitivity: 81%
- Specificity: 98% 3
Setting-Specific Recommendations
General Hospital Settings
- Use the standard CAM for non-intubated, verbal patients
- The CAM may detect more subtle cases of delirium compared to the CAM-ICU in alert, non-intubated patients 4
Intensive Care Units
- Use the CAM-ICU for both ventilated and non-ventilated patients
- The Society of Critical Care Medicine (SCCM) Pain, Agitation, and Delirium guidelines strongly recommend using either CAM-ICU or the Intensive Care Delirium Screening Checklist (ICDSC) 1
- First assess arousal level using a validated sedation scale (Richmond Agitation Sedation Scale or Sedation-Agitation Scale) before performing delirium assessment 1
Neurocritical Care
- Use either the CAM-ICU or ICDSC
- When assessing delirium in neurologically injured patients, search for new neurologic insults in addition to using standard delirium assessment tools 1
- Pay attention to level of wakefulness during screening to avoid confounding due to residual sedative effects 1
Cancer Patients
- The CAM is recommended for delirium assessment in cancer patients 1
- Be particularly vigilant for hypoactive delirium, which is the most common subtype in cancer patients and frequently missed by clinical teams 1
Implementation Best Practices
- Regular screening: Implement routine delirium monitoring for all high-risk patients
- Proper training: Ensure staff are trained in the correct use of the chosen assessment tool
- Consistent application: Use the same tool consistently for a given patient to track changes over time
- Documentation: Document all assessments and communicate findings to the healthcare team
Common Pitfalls to Avoid
- Underdiagnosis: Hypoactive delirium is frequently missed without formal screening tools 1, 5
- Inconsistent assessment: Using different tools or methods across shifts leads to inconsistent detection
- Inadequate training: Improper application of assessment tools reduces their sensitivity and specificity
- Failure to distinguish: Not differentiating between delirium and dementia (delirium has acute onset, fluctuating course, and disordered attention) 5
Clinical Implications
Early and accurate delirium detection is critical as:
- Delirium is associated with increased mortality (at least twofold increase) 1
- Delirium is linked to longer hospital stays and higher institutionalization rates 1, 5
- Early detection enables prompt investigation of underlying causes and implementation of appropriate management strategies 5
By implementing validated delirium assessment tools like the CAM and CAM-ICU, clinicians can significantly improve detection rates and ultimately patient outcomes through timely intervention.