What is the normal duration of a QRS (Quaternary Repolarization Segment) complex?

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Normal QRS Duration

The normal QRS duration in adults is ≤110 ms, with values between 110-119 ms considered borderline or incomplete conduction delay, and ≥120 ms indicating complete conduction delay or bundle branch block. 1

Normal QRS Duration by Age Group

  • Adults: ≤110 ms
  • Children 4-16 years: <100 ms
  • Children <4 years: <90 ms

Abnormal QRS Duration Classifications

Incomplete Conduction Delays

  • Incomplete RBBB: QRS duration between 110-119 ms with RBBB morphology 2
  • Incomplete LBBB: QRS duration between 110-119 ms with LBBB morphology 2

Complete Conduction Delays

  • Complete RBBB: QRS duration ≥120 ms with specific RBBB morphology 2
  • Complete LBBB: QRS duration ≥120 ms with specific LBBB morphology 2
  • Nonspecific intraventricular conduction delay: QRS duration >110 ms without meeting criteria for RBBB or LBBB 2

Clinical Significance of QRS Duration

QRS duration has important prognostic implications:

  • QRS ≥120 ms is associated with:

    • More advanced myocardial disease 3
    • Worse left ventricular function 3, 4
    • Poorer prognosis and higher all-cause mortality 3
    • Increased risk of ventricular tachyarrhythmias 3
  • QRS ≥170 ms with LBBB is strongly associated with significant left ventricular systolic dysfunction (mean EF of 24%) 5

  • Progressive increases in QRS duration correlate with worsening prognosis 3

Measurement Technique

For accurate QRS measurement:

  • Measure from the earliest onset to the latest offset in any lead
  • Use the widest QRS complex for assessment
  • Consider that global intervals (across all leads) are longer than single-lead measurements

Common Pitfalls

  • Failure to consider age-appropriate norms
  • Incorrect measurement technique
  • Not recognizing that QRS duration may increase with increasing heart size
  • Overlooking that fragmented QRS (notched R or S waves with normal duration) may also indicate myocardial pathology 6

QRS prolongation is a valuable diagnostic and prognostic marker in various cardiac conditions, with specific thresholds (110 ms and 120 ms) serving as important clinical decision points.

References

Guideline

Cardiac Cycle Physiology

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Significance of QRS complex duration in patients with heart failure.

Journal of the American College of Cardiology, 2005

Research

[Fragmented QRS. Relevance in clinical practice].

Herzschrittmachertherapie & Elektrophysiologie, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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