What is the best next step for an 8-month-old with a normal cardiac exam and normal SpO2, but a CXR showing a boot-shaped heart?

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Response to Pediatrician Regarding "Boot-Shaped Heart" on CXR in a Healthy 8-Month-Old

Given the normal cardiac exam, normal oxygen saturation, and excellent growth, I recommend proceeding with a targeted echocardiogram to definitively rule out cardiac pathology, though this likely represents a false positive finding.

Assessment of the Current Clinical Picture

The clinical scenario presents a healthy 8-month-old female with:

  • Excellent growth (95th percentile)
  • Normal cardiac exam with no murmur
  • SpO2 of 100%
  • Incidental finding of "boot-shaped heart" on CXR obtained for persistent cough

This constellation of findings creates an interesting clinical situation. A "boot-shaped heart" on CXR typically raises concern for Tetralogy of Fallot (TOF), which classically presents with this radiographic appearance 1. However, the completely normal clinical presentation makes this diagnosis highly unlikely.

Diagnostic Approach

Why an Echocardiogram is Indicated

According to ACC/AHA guidelines, cardiomegaly or abnormal cardiac silhouette on chest radiograph is a Class I indication for echocardiography in pediatric patients 2. Despite the low clinical suspicion, the finding of a "boot-shaped heart" on CXR warrants further evaluation to definitively rule out structural heart disease.

Type of Echocardiogram Needed

A targeted transthoracic echocardiogram would be most appropriate in this case. The European Association of Cardiovascular Imaging guidelines suggest that for screening purposes in children with suspected but unlikely cardiac disease, a basic quantitative evaluation is advised 2. This should include:

  • Left ventricular size and function
  • Right ventricular size and function
  • Valve morphology and function
  • Outflow tract evaluation
  • Aortic dimensions

Rationale for This Approach

  1. Safety and Definitive Diagnosis: An echocardiogram is non-invasive and will provide definitive information about cardiac structure and function 3.

  2. Parental Reassurance: Having a documented normal echocardiogram will provide reassurance to the family and clear documentation in the medical record.

  3. Low Pre-test Probability: The combination of normal growth, normal oxygen saturation, and absence of murmur makes significant congenital heart disease extremely unlikely. TOF typically presents with cyanosis and/or a murmur, neither of which is present in this case.

  4. Avoiding Unnecessary Follow-up: A normal echocardiogram will prevent unnecessary follow-up visits and parental anxiety.

Common Pitfalls to Avoid

  1. Over-interpretation of CXR findings: Chest radiographs can sometimes give the appearance of abnormal cardiac silhouettes due to technical factors such as rotation, inspiration level, or projection angle.

  2. Unnecessary additional testing: If the echocardiogram is normal, no further cardiac testing would be indicated unless the clinical picture changes.

  3. Delayed diagnosis: Although unlikely in this case, missing a cardiac diagnosis could lead to complications if the radiographic finding did represent true pathology.

  4. Communication issues: Ensure clear communication of findings to the family to avoid unnecessary anxiety 4.

In summary, while clinical suspicion for cardiac pathology is low based on the excellent clinical status of this infant, a targeted echocardiogram is the appropriate next step to definitively evaluate the "boot-shaped heart" finding on CXR and provide reassurance to both the clinical team and the family.

References

Research

Tetralogy of Fallot.

Orphanet journal of rare diseases, 2009

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Understanding by General Providers of the Echocardiogram Report.

The American journal of cardiology, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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