Treatment of Diaper Rash
The most effective treatment for diaper rash includes frequent diaper changes, gentle cleansing, application of barrier creams containing zinc oxide or petroleum jelly, and allowing diaper-free time to promote healing. 1
General Treatment Approach
Immediate Interventions
- Change diapers frequently (every 2-3 hours and immediately after bowel movements)
- Gentle cleansing of the diaper area:
- Use warm water with soft cloth or baby wipes
- Avoid rubbing - pat dry instead
- Avoid alcohol-containing wipes that can dry the skin
Barrier Protection
- Apply a thick layer of barrier cream containing zinc oxide or petroleum jelly at every diaper change 1, 2
- Zinc oxide/petrolatum-based formulations have been shown to significantly reduce skin erythema and diaper rash 3
- Apply ointments rather than creams or lotions for better barrier protection
Air Exposure
- Allow diaper-free time several times daily to let the skin breathe and heal
- Place the baby on a clean towel during this time to catch any accidents
Treatment Based on Severity
Mild Diaper Rash
- Continue frequent diaper changes and barrier cream application
- Use superabsorbent disposable diapers with gelling material to keep moisture away from skin 1
- Modify diapers if needed by trimming the inner elastic to reduce friction 1
Moderate to Severe Diaper Rash
- All of the above interventions
- Consider zinc gluconate-containing barrier creams which have shown significant improvement in erythema after 30 days of use 4
- Line the diaper with a soft cloth liner coated with emollient or petroleum jelly to reduce friction 1
Fungal Diaper Rash (Candidal)
- If the rash appears bright red with satellite lesions, consider antifungal treatment
- Apply topical antifungal powder such as nystatin 2-3 times daily until healing is complete 5
- Continue barrier cream application between antifungal treatments
Prevention Strategies
Diaper modifications:
- Use well-fitted diapers to reduce friction
- Consider removing the outer elastic layer around the legs 1
- Use superabsorbent disposable diapers
Skin care practices:
When to Seek Medical Attention
- Rash worsens or doesn't improve after 7 days of home treatment 1
- Signs of infection appear (increased redness, warmth, swelling, drainage)
- Rash spreads beyond the diaper area
- Child develops fever or appears in significant pain 1
Common Pitfalls to Avoid
- Avoid harsh soaps or alcohol-containing products that can irritate the skin
- Avoid talcum powder which can be inhaled and cause respiratory problems
- Don't overtighten diapers as this increases friction and moisture retention
- Avoid over-washing the diaper area which can strip natural oils and worsen irritation
- Don't use adult products containing strong fragrances or chemicals
The ABCDE approach to diaper rash treatment summarizes the key elements: Airing, Barrier application, Cleansing, Diaper selection, and Education of caregivers 6.