Recommended Follow-Up Protocol for Patients with Anorexia Nervosa
Regular follow-up visits every 2-4 weeks are essential for patients with anorexia nervosa to monitor weight, assess for medical complications, evaluate nutritional status, and provide ongoing psychological support. 1
Initial Assessment Components for Follow-Up Visits
Physical Assessment
- Weight measurement (unclothed or in consistent light clothing)
- Vital signs (heart rate, blood pressure, temperature)
- Physical examination focusing on:
- Cardiovascular status (bradycardia, orthostatic hypotension)
- Skin condition (lanugo, dry skin, poor wound healing)
- Peripheral edema
- Muscle wasting
- Dental erosion (if purging behaviors present)
Laboratory Monitoring
- Complete blood count (every 3-6 months)
- Comprehensive metabolic panel including:
- Electrolytes (sodium, potassium, chloride, bicarbonate)
- Liver function tests
- Kidney function (BUN, creatinine)
- Vitamin B12 and folate levels (every 3-6 months)
- Vitamin D levels
- Consider micronutrient testing in patients with:
- Small bowel involvement
- History of significant weight loss
- Prolonged malnutrition
Nutritional Assessment
- Dietary intake evaluation
- Weight trends (gain, loss, or maintenance)
- Eating behaviors and patterns
- Use of compensatory behaviors (purging, excessive exercise)
- Assessment for secondary causes of anorexia
Follow-Up Frequency and Monitoring
Frequency Guidelines
- Severely malnourished patients (BMI ≤14): Weekly visits until medically stable 2
- Moderately malnourished patients (BMI 14-16): Every 2 weeks
- Mild malnutrition or weight-restored patients (BMI ≥16): Every 3-4 weeks
- Adjust frequency based on:
- Clinical stability
- Rate of weight restoration
- Presence of medical complications
- Level of insight 2
Specific Monitoring Parameters
Weight restoration goals:
- Target weight gain of 0.5-1 kg/week for outpatients
- Document weight trajectory at each visit
- Assess for fluid retention that may mask true weight status
Vital sign monitoring:
- Heart rate <50 bpm requires increased monitoring
- Orthostatic hypotension (drop >20 mmHg systolic or >10 mmHg diastolic)
- Temperature <36°C
Psychological assessment:
- Eating disorder thoughts and behaviors
- Anxiety and depression symptoms
- Suicidal ideation
- Body image disturbance
- Insight into illness (strong predictor of recovery) 2
Multidisciplinary Approach
Team Coordination
- Regular communication between:
- Primary care physician
- Psychiatrist/psychologist
- Registered dietitian
- Other specialists as needed (cardiologist, endocrinologist)
Treatment Components to Monitor
Nutritional rehabilitation:
- Progress with meal plan adherence
- Need for nutritional supplements
- Consider appetite stimulants in select cases 3
Psychological interventions:
- Adherence to therapy appointments
- Response to cognitive-behavioral therapy or other modalities
- Family involvement in treatment (especially for adolescents)
Medication management:
- Response to psychiatric medications
- Side effects monitoring
- Medication adherence
Criteria for Level of Care Adjustment
Hospitalization Indicators
- Heart rate <40 bpm
- Blood pressure <90/60 mmHg
- Temperature <35.5°C
- Weight <75% of expected body weight
- Rapid weight loss (>1 kg/week)
- Electrolyte abnormalities
- Suicidal ideation with plan or intent
- Failure of outpatient treatment
Transition to Less Intensive Care
- Medical stability for at least 2 weeks
- Consistent weight gain in outpatient setting
- Improved insight and motivation
- Reduced eating disorder behaviors
- Adequate social support
Long-Term Follow-Up Considerations
Duration of Monitoring
- Continue regular follow-up for at least 2-3 years after weight restoration 4
- Long-term monitoring is essential as recovery from anorexia nervosa can continue over many years 4
- Early recovery is strongly associated with long-term recovery (odds ratio = 10.5) 4
Relapse Prevention
- Identify early warning signs of relapse
- Develop relapse prevention plan
- Maintain connection with treatment team even during periods of stability
- Consider booster sessions during high-risk periods
Special Considerations
Adolescents
- More frequent monitoring (often weekly)
- Growth chart monitoring
- Pubertal development assessment
- Family involvement in treatment and monitoring
Pregnancy
- Increased monitoring frequency
- Coordination with obstetric care
- Nutritional supplementation
- Fetal growth monitoring
Comorbid Medical Conditions
- Diabetes: Monitor blood glucose and insulin requirements
- Gastrointestinal disorders: Assess for malabsorption
- Cardiac abnormalities: Regular ECG monitoring
Documentation Template for Follow-Up Visits
Vital signs and anthropometrics:
- Weight, BMI, vital signs
- Comparison to previous measurements
Nutritional status:
- Current dietary intake
- Eating behaviors
- Supplement use
Medical assessment:
- Physical examination findings
- Laboratory results
- Medical complications
Psychological status:
- Eating disorder thoughts/behaviors
- Mood, anxiety
- Insight and motivation
Treatment plan:
- Adjustments to meal plan
- Medication changes
- Psychological interventions
- Next appointment timing
By implementing this structured follow-up protocol, clinicians can effectively monitor patients with anorexia nervosa, detect complications early, and support long-term recovery. The evidence shows that recovery can continue over many years, with approximately two-thirds of patients achieving recovery with appropriate long-term care 4.