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Differential Diagnosis for Patient with Mild Abdominal Pain, Nausea, Vomiting, Negative Abdominal CT, High White Count, and Septic Vitals

  • Single Most Likely Diagnosis
    • Appendicitis: Despite a negative abdominal CT, appendicitis remains a high consideration due to the clinical presentation of abdominal pain, nausea, vomiting, and elevated white blood cell count. Early appendicitis or a retrocecal appendix might not be visible on CT.
  • Other Likely Diagnoses
    • Diverticulitis: Although the CT was negative, diverticulitis, especially if it's early or limited, might not show clear signs on imaging. The symptoms and elevated white count support this possibility.
    • Gastroenteritis: Could present with similar symptoms, including abdominal pain, nausea, vomiting, and an elevated white count if there's a significant inflammatory response.
    • Mesenteric Lymphadenitis: Often mimics appendicitis and can have a similar presentation, including abdominal pain and elevated white blood cell count.
  • Do Not Miss Diagnoses
    • Mesenteric Ischemia: This is a critical diagnosis to consider due to its high mortality rate if not promptly treated. The presence of septic-looking vitals and abdominal pain, despite a negative CT, warrants consideration of this diagnosis.
    • Ectopic Pregnancy: In women of childbearing age, ectopic pregnancy must be ruled out, as it can present with abdominal pain and vomiting, and a negative CT does not exclude this diagnosis.
    • Intestinal Obstruction: Can lead to severe consequences if not addressed promptly. Early obstruction might not show significant findings on CT, especially if it's a partial obstruction.
  • Rare Diagnoses
    • Intussusception: More common in children but can occur in adults, often with a lead point such as a tumor. It can cause abdominal pain, nausea, and vomiting.
    • Ovarian Torsion: Another rare but critical diagnosis in women, which can present with acute abdominal pain and vomiting.
    • Primary Epiploic Appendagitis: A rare condition that can mimic appendicitis or diverticulitis, often resolving on its own but can cause significant pain and elevated inflammatory markers.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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