What is the proper procedure for inserting a central line?

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Last updated: September 25, 2025View editorial policy

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Central Line Insertion Procedure

The proper procedure for inserting a central line requires real-time ultrasound guidance with strict aseptic technique, including maximal barrier precautions, to minimize complications and infection risk. 1

Pre-Procedure Preparation

  • Ensure proper education and training for all personnel involved in central venous catheter placement 2

  • Gather standardized equipment set including:

    • Ultrasound machine with sterile probe cover
    • Central line kit with appropriate catheter size (select smallest size appropriate for clinical situation) 2, 1
    • Sterile supplies for maximal barrier precautions
    • Chlorhexidine-containing antiseptic solution (>0.5%) 2
  • Implement maximal barrier precautions:

    • Hand hygiene (soap and water or alcohol-based hand rubs) 2
    • Sterile cap, mask covering both mouth and nose 2
    • Sterile gown and gloves 2
    • Full-body patient drape 2
    • Eye protection 2

Site Selection and Patient Positioning

  • Select insertion site based on clinical need 2:

    • Prefer internal jugular vein (first choice) due to lower insertion-related complications 1
    • Subclavian vein (second choice)
    • Avoid femoral vein when possible (higher infection/thrombosis risk) 1
    • Right-sided placement generally preferred to reduce malposition risk 1
    • Avoid contaminated sites (burns, infections, inguinal area, adjacent to tracheostomy or surgical wounds) 2
  • Position patient appropriately:

    • Trendelenburg position for neck/chest access when clinically feasible 2, 1
    • Reverse Trendelenburg for femoral access 1

Skin Preparation

  • Apply alcoholic chlorhexidine solution (>0.5%) for skin antisepsis 2
  • Allow antiseptic to completely dry before puncture 1
  • If chlorhexidine is contraindicated, use povidone-iodine or alcohol 2, 1

Ultrasound-Guided Insertion Technique

  1. Vessel Identification:

    • Use real-time ultrasound guidance for vessel localization and venipuncture (mandatory for internal jugular vein) 2
    • Examine in both short-axis (transverse) and long-axis (longitudinal) views 1
    • Use compression ultrasound to exclude thrombosis and color Doppler to differentiate veins from arteries 1
  2. Venous Access:

    • For subclavian approach, use thin-wall needle (Seldinger) technique 2
    • For jugular/femoral approach, select thin-wall needle or catheter-over-needle technique based on clinical situation and operator experience 2
    • Visualize needle tip throughout procedure to avoid posterior wall puncture 1
  3. Wire and Catheter Placement (Seldinger Technique):

    • After successful venipuncture, thread guidewire through needle 3
    • Verify correct guidewire position in vein using ultrasound 1
    • Remove needle while maintaining guidewire position
    • Make small skin incision at entry site if needed
    • Thread dilator over guidewire to create tract
    • Remove dilator while maintaining guidewire position
    • Thread catheter over guidewire to desired depth
    • Remove guidewire while maintaining catheter position
    • Aspirate and flush all lumens to confirm patency
  4. Confirmation of Placement:

    • Verify catheter tip position with chest X-ray or other imaging methods 1
    • Ideal tip position: lower third of superior vena cava, at atrio-caval junction, or upper right atrium 1

Catheter Securement and Maintenance

  • Apply sterile transparent dressing over insertion site 2, 1
  • Secure catheter with sutureless securement device 1
  • Replace dressing weekly (or when soiled/loose) 2, 1
  • Clean access ports with appropriate antiseptic before each use 1
  • Perform daily assessment of catheter necessity 1
  • Maintain catheter patency through routine flushing 1

Complication Prevention and Management

  • If arterial puncture occurs, leave the dilator or catheter in place and immediately consult surgical specialists 2
  • Monitor for signs of infection and remove catheter if CLABSI is suspected 1
  • Consider antimicrobial-coated catheters for high-risk patients 2, 1
  • Daily skin cleansing with 2% chlorhexidine-impregnated wash cloth can reduce infection risk 2

Critical Pitfalls to Avoid

  • Failure to use real-time ultrasound guidance (increases complication risk) 1
  • Inadequate sterile barrier precautions (increases infection risk) 4
  • Improper patient positioning (increases risk of air embolism) 1
  • Multiple insertion attempts (increases complication risk) 2
  • Improper catheter tip position (increases thrombotic complications) 1
  • Delayed catheter removal when no longer needed (increases infection risk) 2, 1

Implementation of a comprehensive care bundle for central line insertion has been shown to significantly reduce central line-associated bloodstream infections (CLABSIs) 5, making strict adherence to these guidelines essential for patient safety.

References

Guideline

Central Venous Catheter Placement and Maintenance

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Sven Ivar Seldinger: catheter introduction on a flexible leader.

The Journal of emergency medicine, 1990

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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