From the Research
The maximum recommended dose of Cordyceps sinensis is 3,000 mg per day, as no dose-dependent increase in toxicity was detected in studies, and the median lethal dose (LD50) was greater than 5 g/kg, indicating a non-toxic level 1.
Key Considerations
- The dose of 500 mg three times a day has been shown to be effective in patients with mild to moderate COVID-19 infection, with a relatively shorter time for improvement of clinical symptoms and a higher number of patients showing negative RT-PCR tests on day 10 2.
- Cordyceps supplements should be taken with food to improve absorption and reduce potential stomach discomfort.
- The safety profile of cordyceps hasn't been extensively studied for long-term use, so it's advisable to take periodic breaks from supplementation.
- People with autoimmune conditions, those on immunosuppressants, blood thinners, or diabetes medications should consult with a healthcare provider before taking cordyceps due to potential interactions.
Bioactive Compounds and Mechanisms
- Cordyceps contains bioactive compounds like cordycepin and polysaccharides that may support immune function, increase ATP production for energy, and provide antioxidant effects.
- The exact mechanisms and optimal dosing of cordyceps are not yet fully understood and require further research.
Dosage and Administration
- Start with a lower dose (around 500-1,000 mg daily) and gradually increase as needed while monitoring for any side effects.
- Divide the daily dose into 2-3 doses to maintain a consistent level of bioactive compounds in the body.
- Consider consulting with a healthcare provider to determine the best dosage and administration schedule for individual needs.