What is the most common site for accessory splenic tissue?

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Last updated: September 26, 2025View editorial policy

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Most Common Site for Accessory Splenic Tissue

The most common site for accessory splenic tissue is the splenic hilum (option c). 1, 2, 3, 4

Anatomical Distribution of Accessory Spleens

Accessory spleens (splenules) are found in approximately 10-30% of the general population 1. The distribution of accessory splenic tissue follows a clear pattern:

  • Splenic hilum: 75% of accessory spleens are located at the splenic hilum 2
  • Pancreatic tail region: Almost 20% of accessory spleens are found in or near the pancreatic tail 3
  • Other locations: Less commonly found in the:
    • Gastrosplenic ligament
    • Splenocolic ligament
    • Greater omentum
    • Pelvis (extremely rare) 4

Clinical Significance

Understanding the location of accessory splenic tissue is important for several clinical scenarios:

  1. Post-splenectomy recurrence of hematologic disease: Missed accessory spleens can cause recurrence of conditions like idiopathic thrombocytopenic purpura after splenectomy 2, 5

  2. Diagnostic challenges: Accessory spleens can mimic:

    • Pancreatic tumors (when located near pancreatic tail)
    • Lymphadenopathy
    • Adrenal masses
    • Metastatic disease 3, 6
  3. Surgical considerations: During splenectomy for hematologic disorders, identification and removal of accessory spleens is critical to prevent disease recurrence 2

Detection Methods

  • Laparoscopic exploration: Superior sensitivity (100%) for detecting accessory spleens compared to preoperative imaging 2
  • CT/MRI: Sensitivity of 90-95% for detecting splenules, but may miss smaller accessory spleens 1
  • Nuclear medicine scans: Particularly useful for confirming suspected accessory splenic tissue 6

Key Points to Remember

  • Accessory spleens are common anatomical variants
  • The splenic hilum is by far the most common location
  • They are typically asymptomatic but can become clinically significant after splenectomy
  • Imaging studies may misidentify accessory spleens as tumors or miss them entirely
  • Direct visualization during surgery remains the gold standard for identification

References

Guideline

Splenules and Accessory Spleens

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Intrapancreatic accessory spleen.

Radiology case reports, 2010

Research

Symptomatic pelvic accessory spleen.

American journal of surgery, 2007

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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